Formate Promotes <italic toggle="yes">Shigella</italic> Intercellular Spread and Virulence Gene Expression

Formate Promotes <italic toggle="yes">Shigella</italic> Intercellular Spread and Virulence Gene Expression

ABSTRACT The intracellular human pathogen Shigella flexneri invades the colon epithelium, replicates to high cell density within the host cell, and then spreads to adjacent epithelial cells. When S. flexneri gains access to the host cytosol, the bacteria metabolize host cytosolic carbon using glycol...

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Bibliographic Details
Main Authors: Benjamin J. Koestler, Carolyn R. Fisher, Shelley M. Payne
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
Shigella
formate
metabolism
virulence regulation
Online Access:https://journals.asm.org/doi/10.1128/mBio.01777-18

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