Foot-and-Mouth Disease Virus Lacking the Leader Protein and Containing Two Negative DIVA Markers (FMDV LL3B3D A<sub>24</sub>) Is Highly Attenuated in Pigs

Inactivated whole-virus vaccines are widely used for the control of foot-and-mouth disease (FMD). Their production requires the growth of large quantities of virulent FMD virus in biocontainment facilities, which is expensive and carries the risk of an inadvertent release of virus. Attenuated recomb...

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Main Authors: Michael Eschbaumer, Veronika Dill, Jolene C. Carlson, Jonathan Arzt, Carolina Stenfeldt, Peter W. Krug, John M. Hardham, Jacob E. Stegner, Luis L. Rodriguez, Elizabeth Rieder
פורמט: Article
שפה:English
יצא לאור: MDPI AG 2020-02-01
סדרה:Pathogens
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גישה מקוונת:https://www.mdpi.com/2076-0817/9/2/129