Do testosterone and sex hormone-binding globulin affect cancer risk? A Mendelian randomization and bioinformatics study

Do testosterone and sex hormone-binding globulin affect cancer risk? A Mendelian randomization and bioinformatics study

AbstractUsing Mendelian Randomization (MR) and large-scale Genome-Wide Association Study (GWAS) data, this study aimed to investigate the potential causative relationship between testosterone and sex hormone-binding globulin (SHBG) levels and the onset of several cancers, including pathway enrichmen...

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Bibliographic Details
Main Authors: Xiwen Liu, Lixuan Lin, Qi Cai, Caichen Li, Haoxiang Xu, Ruiqi Zeng, Mingtong Zhang, Xinyi Qiu, Shiqi Chen, Xizhe Zhang, Linchong Huang, Wenhua Liang, Jianxing He
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:The Aging Male
Subjects:
Sex hormone binding globulin
testosterone
cancer
mendelian randomization
bioinformatical analysis
Online Access:https://www.tandfonline.com/doi/10.1080/13685538.2023.2261524

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