Validation of a modified fluorimetric assay for the screening of trichomonacidal drugs

Validation of a modified fluorimetric assay for the screening of trichomonacidal drugs

A fluorimetric microassay that uses a redox dye to determine the viability of the flagellate Trichomonas vaginalis has been optimised to provide a more sensitive method to evaluate potential trichomonacidal compounds. Resazurin has been used in recent years to test drugs against different parasites,...

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Bibliographic Details
Main Authors:	Alexandra Ibáñez Escribano, Alfredo Meneses Marcel, Yanetsy Machado Tugores, Juan José Nogal Ruiz, Vicente J Arán Redó, José Antonio Escario García-Trevijano, Alicia Gómez Barrio
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2012-08-01
Series:	Memorias do Instituto Oswaldo Cruz
Subjects:	Trichomonas vaginalis antitrichomonal agents drug screening assay resazurin high-throughput screening assays
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000500010&lng=en&tlng=en

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