The RNA Capping Enzyme Domain in Protein A is Essential for Flock House Virus Replication

The RNA Capping Enzyme Domain in Protein A is Essential for Flock House Virus Replication

The nodavirus flock house virus (FHV) and the alphavirus Semliki Forest virus (SFV) show evolutionarily intriguing similarities in their replication complexes and RNA capping enzymes. In this study, we first established an efficient FHV trans-replication system in mammalian cells, which disjoins pro...

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Bibliographic Details
Main Authors: Tania Quirin, Yu Chen, Maija K. Pietilä, Deyin Guo, Tero Ahola
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Viruses
Subjects:
RNA replication
nodavirus
alphavirus
RNA capping enzyme
replication complex
Online Access:http://www.mdpi.com/1999-4915/10/9/483

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