A case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by ChAdOx1 nCoV-19 COVID-19 vaccine
Although enteric fever is a relatively common disease in countries mainly belonging to South Asia (incidence of around 100/100,000 persons per year) where there is poor hygiene, its complications in the form of hemophagocytic lymphohistiocytosis (HLH) are rare but have been documented before. Here,...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Current Research in Scientific Medicine |
| Subjects: | |
| Online Access: | http://www.jcrsmed.org/article.asp?issn=2455-3069;year=2022;volume=8;issue=1;spage=81;epage=84;aulast=Cherian |
| _version_ | 1798038431227445248 |
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| author | Mathew Cherian Siddhant Jeevan Thampi |
| author_facet | Mathew Cherian Siddhant Jeevan Thampi |
| author_sort | Mathew Cherian |
| collection | DOAJ |
| description | Although enteric fever is a relatively common disease in countries mainly belonging to South Asia (incidence of around 100/100,000 persons per year) where there is poor hygiene, its complications in the form of hemophagocytic lymphohistiocytosis (HLH) are rare but have been documented before. Here, we present the case of a 19-year-old boy diagnosed with enteric fever with secondary HLH possibly induced by the COVID-19 vaccine (COVISHIELD ChAdOx1 nCoV-19 coronavirus vaccine [Recombinant]). Although there is no proof that the vaccine could have induced secondary HLH, its possibility cannot be ruled out simultaneously. Early identification and diagnosis of HLH are of extreme importance. If not treated correctly, mortality can reach up to 40%. In this article, we would like to press upon the clinical presentation, diagnosis, and management of such a case and the possibility of this presentation being induced by the COVID-19 vaccine. |
| first_indexed | 2024-04-11T21:40:06Z |
| format | Article |
| id | doaj.art-3d60cde11ad54b309a420f7e4a447d2e |
| institution | Directory Open Access Journal |
| issn | 2455-3069 |
| language | English |
| last_indexed | 2024-04-11T21:40:06Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Current Research in Scientific Medicine |
| spelling | doaj.art-3d60cde11ad54b309a420f7e4a447d2e2022-12-22T04:01:37ZengWolters Kluwer Medknow PublicationsJournal of Current Research in Scientific Medicine2455-30692022-01-0181818410.4103/jcrsm.jcrsm_94_21A case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by ChAdOx1 nCoV-19 COVID-19 vaccineMathew CherianSiddhant Jeevan ThampiAlthough enteric fever is a relatively common disease in countries mainly belonging to South Asia (incidence of around 100/100,000 persons per year) where there is poor hygiene, its complications in the form of hemophagocytic lymphohistiocytosis (HLH) are rare but have been documented before. Here, we present the case of a 19-year-old boy diagnosed with enteric fever with secondary HLH possibly induced by the COVID-19 vaccine (COVISHIELD ChAdOx1 nCoV-19 coronavirus vaccine [Recombinant]). Although there is no proof that the vaccine could have induced secondary HLH, its possibility cannot be ruled out simultaneously. Early identification and diagnosis of HLH are of extreme importance. If not treated correctly, mortality can reach up to 40%. In this article, we would like to press upon the clinical presentation, diagnosis, and management of such a case and the possibility of this presentation being induced by the COVID-19 vaccine.http://www.jcrsmed.org/article.asp?issn=2455-3069;year=2022;volume=8;issue=1;spage=81;epage=84;aulast=Cheriancovid-19 vaccineenteric feverhemophagocytic lymphohistiocytosis |
| spellingShingle | Mathew Cherian Siddhant Jeevan Thampi A case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by ChAdOx1 nCoV-19 COVID-19 vaccine Journal of Current Research in Scientific Medicine covid-19 vaccine enteric fever hemophagocytic lymphohistiocytosis |
| title | A case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by ChAdOx1 nCoV-19 COVID-19 vaccine |
| title_full | A case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by ChAdOx1 nCoV-19 COVID-19 vaccine |
| title_fullStr | A case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by ChAdOx1 nCoV-19 COVID-19 vaccine |
| title_full_unstemmed | A case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by ChAdOx1 nCoV-19 COVID-19 vaccine |
| title_short | A case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by ChAdOx1 nCoV-19 COVID-19 vaccine |
| title_sort | case of enteric fever complicated by hemophagocytic lymphohistiocytosis probably induced by chadox1 ncov 19 covid 19 vaccine |
| topic | covid-19 vaccine enteric fever hemophagocytic lymphohistiocytosis |
| url | http://www.jcrsmed.org/article.asp?issn=2455-3069;year=2022;volume=8;issue=1;spage=81;epage=84;aulast=Cherian |
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