Hypermethylation of MGMT and DAPK gene promoters is associated with tumorigenesis and metastasis in oral squamous cell carcinoma
Background/purpose: Oral squamous cell carcinoma (OSCC) is the fourth major cause of mortality among males in Asia. The tumorigenesis of OSCC is a multi-step process characterized by sequential morphological changes. The extent of lymph node metastasis is a major determinant in the prognosis of canc...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-09-01
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Series: | Journal of Dental Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1991790211000560 |