Reduction in erosive tooth wear using stannous fluoride-containing dentifrices: a meta-analysis
Abstract Dentifrices containing different active agents may be helpful to allow rehardening and to increase the resistance of the eroded surface to further acids or mechanical impacts. This study aimed to compare the effects of conventional (sodium fluoride [NaF]) and stannous fluoride (SnF2)-contai...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Pesquisa Odontológica
2021-11-01
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| Series: | Brazilian Oral Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242021000100951&tlng=en |
| _version_ | 1818949249495203840 |
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| author | Giorgio Aldigueri TRENTIN Laura Teixeira MENDES Bruna Soares da SILVA Luciano CASAGRANDE Fernando Borba de ARAUJO Tathiane Larissa LENZI |
| author_facet | Giorgio Aldigueri TRENTIN Laura Teixeira MENDES Bruna Soares da SILVA Luciano CASAGRANDE Fernando Borba de ARAUJO Tathiane Larissa LENZI |
| author_sort | Giorgio Aldigueri TRENTIN |
| collection | DOAJ |
| description | Abstract Dentifrices containing different active agents may be helpful to allow rehardening and to increase the resistance of the eroded surface to further acids or mechanical impacts. This study aimed to compare the effects of conventional (sodium fluoride [NaF]) and stannous fluoride (SnF2)-containing dentifrices on reducing erosive tooth wear (ETW). The PubMed/MEDLINE, Scopus, LILACS, BBO, EMBASE, TRIP electronic databases, and grey literature were searched until January 2021 to retrieve relevant in vitro and in situ studies related to research question. There were no restrictions on publication year or language. Two authors independently selected the studies, extracted the data, and assessed the risk of bias. ETW data were pooled to calculate and compare both dentifrices (overall analysis) and in vitro and in situ studies separately (subgroup analysis). Statistical analyses were performed using RevMan5.3 with a random effects model. Of 820 potentially eligible studies, 101 were selected for full-text analysis, and 8 were included in the systematic review and meta-analysis. There was a significant difference between SnF2-containing dentifrices and NaF dentifrices only for in vitro studies (p=0.04), showing a higher effect of the SnF2-containing dentifrices against the erosion/abrasion (effect size: -6.80 95%CI: -13.42; -0.19). Most in vitro and in situ studies had high and low risk of bias, respectively. In vitro literature suggests that the ETW reduction is greater when using SnF2-containing dentifrices instead NaF-containing dentifrices. However, the evidence level is insufficient for definitive conclusions. Clinical trials are necessary for a better understanding of the effect of these compounds on ETW. |
| first_indexed | 2024-12-20T08:59:42Z |
| format | Article |
| id | doaj.art-3d651947752648fb911193b46a2c6387 |
| institution | Directory Open Access Journal |
| issn | 1807-3107 |
| language | English |
| last_indexed | 2024-12-20T08:59:42Z |
| publishDate | 2021-11-01 |
| publisher | Sociedade Brasileira de Pesquisa Odontológica |
| record_format | Article |
| series | Brazilian Oral Research |
| spelling | doaj.art-3d651947752648fb911193b46a2c63872022-12-21T19:45:54ZengSociedade Brasileira de Pesquisa OdontológicaBrazilian Oral Research1807-31072021-11-013510.1590/1807-3107bor-2021.vol35.0114Reduction in erosive tooth wear using stannous fluoride-containing dentifrices: a meta-analysisGiorgio Aldigueri TRENTINhttps://orcid.org/0000-0002-5905-5749Laura Teixeira MENDEShttps://orcid.org/0000-0002-8003-9217Bruna Soares da SILVAhttps://orcid.org/0000-0002-1815-7650Luciano CASAGRANDEhttps://orcid.org/0000-0001-9515-6048Fernando Borba de ARAUJOhttps://orcid.org/0000-0001-5957-4891Tathiane Larissa LENZIhttps://orcid.org/0000-0003-3568-5217Abstract Dentifrices containing different active agents may be helpful to allow rehardening and to increase the resistance of the eroded surface to further acids or mechanical impacts. This study aimed to compare the effects of conventional (sodium fluoride [NaF]) and stannous fluoride (SnF2)-containing dentifrices on reducing erosive tooth wear (ETW). The PubMed/MEDLINE, Scopus, LILACS, BBO, EMBASE, TRIP electronic databases, and grey literature were searched until January 2021 to retrieve relevant in vitro and in situ studies related to research question. There were no restrictions on publication year or language. Two authors independently selected the studies, extracted the data, and assessed the risk of bias. ETW data were pooled to calculate and compare both dentifrices (overall analysis) and in vitro and in situ studies separately (subgroup analysis). Statistical analyses were performed using RevMan5.3 with a random effects model. Of 820 potentially eligible studies, 101 were selected for full-text analysis, and 8 were included in the systematic review and meta-analysis. There was a significant difference between SnF2-containing dentifrices and NaF dentifrices only for in vitro studies (p=0.04), showing a higher effect of the SnF2-containing dentifrices against the erosion/abrasion (effect size: -6.80 95%CI: -13.42; -0.19). Most in vitro and in situ studies had high and low risk of bias, respectively. In vitro literature suggests that the ETW reduction is greater when using SnF2-containing dentifrices instead NaF-containing dentifrices. However, the evidence level is insufficient for definitive conclusions. Clinical trials are necessary for a better understanding of the effect of these compounds on ETW.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242021000100951&tlng=enTooth ErosionTooth AbrasionTin FluoridesFluoride DentifricesSystematic Review |
| spellingShingle | Giorgio Aldigueri TRENTIN Laura Teixeira MENDES Bruna Soares da SILVA Luciano CASAGRANDE Fernando Borba de ARAUJO Tathiane Larissa LENZI Reduction in erosive tooth wear using stannous fluoride-containing dentifrices: a meta-analysis Brazilian Oral Research Tooth Erosion Tooth Abrasion Tin Fluorides Fluoride Dentifrices Systematic Review |
| title | Reduction in erosive tooth wear using stannous fluoride-containing dentifrices: a meta-analysis |
| title_full | Reduction in erosive tooth wear using stannous fluoride-containing dentifrices: a meta-analysis |
| title_fullStr | Reduction in erosive tooth wear using stannous fluoride-containing dentifrices: a meta-analysis |
| title_full_unstemmed | Reduction in erosive tooth wear using stannous fluoride-containing dentifrices: a meta-analysis |
| title_short | Reduction in erosive tooth wear using stannous fluoride-containing dentifrices: a meta-analysis |
| title_sort | reduction in erosive tooth wear using stannous fluoride containing dentifrices a meta analysis |
| topic | Tooth Erosion Tooth Abrasion Tin Fluorides Fluoride Dentifrices Systematic Review |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242021000100951&tlng=en |
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