The progress and development of antidepressants
Major depressive disorder is a common emotional mood disorder disease, which mainly manifests as depression, cognitive impairment, weakened volition activities, loss of appetite, and sleep disorders. Depression is a common mental disorder affecting more than 264 million people worldwide. There are m...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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EDP Sciences
2021-01-01
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| Series: | E3S Web of Conferences |
| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/84/e3sconf_msetee2021_02016.pdf |
| _version_ | 1818736228831330304 |
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| author | Li Keyang Diao Shiqi |
| author_facet | Li Keyang Diao Shiqi |
| author_sort | Li Keyang |
| collection | DOAJ |
| description | Major depressive disorder is a common emotional mood disorder disease, which mainly manifests as depression, cognitive impairment, weakened volition activities, loss of appetite, and sleep disorders. Depression is a common mental disorder affecting more than 264 million people worldwide. There are many antidepressant drugs in clinic, e.g., tricyclic antidepressants, monoamine oxidase inhibitors, selective serotonin (5-HT) reuptake inhibitors and selective norepinephrine (NA) reuptake inhibitors. Although great progress has been made in the research of new antidepressant drugs, the current clinical use of drugs still has many shortcomings, e.g., the unmet efficiency, slow onset of action, and multiple adverse reactions, which are difficult to meet the requirements of the increasing number of the depressed patients. This article mainly focuses on the development process of antidepressant drugs and compares their effects. Specifically, the N-methyl-D-aspartate receptor as a new antidepressant has a good effect, which is worthy of further study. These results shed light for providing a research idea for the study of new antidepressants. |
| first_indexed | 2024-12-18T00:33:49Z |
| format | Article |
| id | doaj.art-3d656edb6e66435fb8e5bee9c53bda1a |
| institution | Directory Open Access Journal |
| issn | 2267-1242 |
| language | English |
| last_indexed | 2024-12-18T00:33:49Z |
| publishDate | 2021-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj.art-3d656edb6e66435fb8e5bee9c53bda1a2022-12-21T21:27:04ZengEDP SciencesE3S Web of Conferences2267-12422021-01-013080201610.1051/e3sconf/202130802016e3sconf_msetee2021_02016The progress and development of antidepressantsLi Keyang0Diao Shiqi1School of Biological Engineering, Nanjing Tech UniversitySchool of Department of cell biology, University of AlbertaMajor depressive disorder is a common emotional mood disorder disease, which mainly manifests as depression, cognitive impairment, weakened volition activities, loss of appetite, and sleep disorders. Depression is a common mental disorder affecting more than 264 million people worldwide. There are many antidepressant drugs in clinic, e.g., tricyclic antidepressants, monoamine oxidase inhibitors, selective serotonin (5-HT) reuptake inhibitors and selective norepinephrine (NA) reuptake inhibitors. Although great progress has been made in the research of new antidepressant drugs, the current clinical use of drugs still has many shortcomings, e.g., the unmet efficiency, slow onset of action, and multiple adverse reactions, which are difficult to meet the requirements of the increasing number of the depressed patients. This article mainly focuses on the development process of antidepressant drugs and compares their effects. Specifically, the N-methyl-D-aspartate receptor as a new antidepressant has a good effect, which is worthy of further study. These results shed light for providing a research idea for the study of new antidepressants.https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/84/e3sconf_msetee2021_02016.pdf |
| spellingShingle | Li Keyang Diao Shiqi The progress and development of antidepressants E3S Web of Conferences |
| title | The progress and development of antidepressants |
| title_full | The progress and development of antidepressants |
| title_fullStr | The progress and development of antidepressants |
| title_full_unstemmed | The progress and development of antidepressants |
| title_short | The progress and development of antidepressants |
| title_sort | progress and development of antidepressants |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2021/84/e3sconf_msetee2021_02016.pdf |
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