The Effect of Diclofenac Sodium-Loaded Poly(Lactide-co-Glycolide) Rods on Bone Formation and Inflammation: A Histological and Histomorphometric Study in the Femora of Rats

The Effect of Diclofenac Sodium-Loaded Poly(Lactide-co-Glycolide) Rods on Bone Formation and Inflammation: A Histological and Histomorphometric Study in the Femora of Rats

Implants made of poly(lactide-co-glycolide) (PLGA) are biodegradable and frequently provoke foreign body reactions (FBR) in the host tissue. In order to modulate the inflammatory response of the host tissue, PLGA implants can be loaded with anti-inflammatory drugs. The aim of this study was to analy...

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Bibliographic Details
Main Authors:	Karoline M. Reich, Petrus Viitanen, Ehsanul Hoque Apu, Stefan Tangl, Nureddin Ashammakhi
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Series:	Micromachines
Subjects:	biodegradable inflammation foreign body reaction multi-nucleated giant cells non-steroidal anti-inflammatory drug
Online Access:	https://www.mdpi.com/2072-666X/11/12/1098

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