Loss of Peter Pan (PPAN) Affects Mitochondrial Homeostasis and Autophagic Flux

Loss of Peter Pan (PPAN) Affects Mitochondrial Homeostasis and Autophagic Flux

Nucleolar stress is a cellular response to inhibition of ribosome biogenesis or nucleolar disruption leading to cell cycle arrest and/or apoptosis. Emerging evidence points to a tight connection between nucleolar stress and autophagy as a mechanism underlying various diseases such as neurodegenerati...

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Bibliographic Details
Main Authors: David P. Dannheisig, Eileen Beck, Enrico Calzia, Paul Walther, Christian Behrends, Astrid S. Pfister
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
apoptosis
autophagy
mitochondria
mitophagy
nucleolus
nucleolar stress
Parkin
PPAN
ribosome
Wnt target
Online Access:https://www.mdpi.com/2073-4409/8/8/894

Internet

https://www.mdpi.com/2073-4409/8/8/894

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