A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal models
The aim of the study was to compare the analgesic activities of ethanolic extract of fruits and whole plant of Fragaria vesca in experimental animal models. The extracts were prepared by percolation method and oral toxicity testing was performed as per OECD guidelines. Analgesic activity was assesse...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Bangladesh Pharmacological Society
2009-06-01
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| Series: | Bangladesh Journal of Pharmacology |
| Subjects: | |
| Online Access: | http://www.bdjpharmacol.com/0401/35.pdf |
| _version_ | 1818042842929430528 |
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| author | Lalit Kanodia Swarnamoni Das |
| author_facet | Lalit Kanodia Swarnamoni Das |
| author_sort | Lalit Kanodia |
| collection | DOAJ |
| description | The aim of the study was to compare the analgesic activities of ethanolic extract of fruits and whole plant of Fragaria vesca in experimental animal models. The extracts were prepared by percolation method and oral toxicity testing was performed as per OECD guidelines. Analgesic activity was assessed by tail flickmethod (for central action) and acetic acid-induced writhing test (for peripheral action). Fruit extract, whole plant extract and aspirin showed significant analgesic activity, both central and peripheral, as compared to control (p< 0.01). Although fruit extract at dose of 500 mg/kg showed better activity than 250 mg/kg (p<0.05). Analgesic activities of fruit extract 250 mg/kg and whole plantextract 500 mg/kg were almost equivalent while aspirin was most potent among all with significantly greater activities as compared to all the extracts (p<0.05). |
| first_indexed | 2024-12-10T08:52:45Z |
| format | Article |
| id | doaj.art-3d6a48afa5b8495fa566b76aa3018d96 |
| institution | Directory Open Access Journal |
| issn | 1991-007X 1991-0088 |
| language | English |
| last_indexed | 2024-12-10T08:52:45Z |
| publishDate | 2009-06-01 |
| publisher | Bangladesh Pharmacological Society |
| record_format | Article |
| series | Bangladesh Journal of Pharmacology |
| spelling | doaj.art-3d6a48afa5b8495fa566b76aa3018d962022-12-22T01:55:31ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-007X1991-00882009-06-01413538A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal modelsLalit KanodiaSwarnamoni DasThe aim of the study was to compare the analgesic activities of ethanolic extract of fruits and whole plant of Fragaria vesca in experimental animal models. The extracts were prepared by percolation method and oral toxicity testing was performed as per OECD guidelines. Analgesic activity was assessed by tail flickmethod (for central action) and acetic acid-induced writhing test (for peripheral action). Fruit extract, whole plant extract and aspirin showed significant analgesic activity, both central and peripheral, as compared to control (p< 0.01). Although fruit extract at dose of 500 mg/kg showed better activity than 250 mg/kg (p<0.05). Analgesic activities of fruit extract 250 mg/kg and whole plantextract 500 mg/kg were almost equivalent while aspirin was most potent among all with significantly greater activities as compared to all the extracts (p<0.05).http://www.bdjpharmacol.com/0401/35.pdfAnalgesicFragaria vescaPercolationTail flickWrithing |
| spellingShingle | Lalit Kanodia Swarnamoni Das A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal models Bangladesh Journal of Pharmacology Analgesic Fragaria vesca Percolation Tail flick Writhing |
| title | A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal models |
| title_full | A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal models |
| title_fullStr | A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal models |
| title_full_unstemmed | A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal models |
| title_short | A comparative study of analgesic property of whole plant and fruit extracts of Fragaria vesca in experimental animal models |
| title_sort | comparative study of analgesic property of whole plant and fruit extracts of fragaria vesca in experimental animal models |
| topic | Analgesic Fragaria vesca Percolation Tail flick Writhing |
| url | http://www.bdjpharmacol.com/0401/35.pdf |
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