Podocalyxin‐Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway

Podocalyxin‐Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway

Abstract Deciphering signaling mechanisms critical for the extended pluripotent stem cell (EPSC) state and primed pluripotency is necessary for understanding embryonic development. Here, a membrane protein, podocalyxin‐like protein 1 (PODXL) as being essential for extended and primed pluripotency, i...

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Main Authors: Wei‐Ju Chen, Wei‐Kai Huang, Sarshan R. Pather, Wei‐Fang Chang, Li‐Ying Sung, Han‐Chung Wu, Mei‐Ying Liao, Chi‐Chiu Lee, Hsuan‐Hui Wu, Chung‐Yi Wu, Kuo‐Shiang Liao, Chun‐Yu Lin, Shang‐Chih Yang, Hsuan Lin, Pei‐Lun Lai, Chi‐Hou Ng, Chun‐Mei Hu, I‐Chih Chen, Chi‐Hsuan Chuang, Chien‐Ying Lai, Po‐Yu Lin, Yueh‐Chang Lee, Scott C. Schuyler, Axel Schambach, Frank Leigh Lu, Jean Lu
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Advanced Science
Subjects:
cholesterol
extended pluripotency
integrin
podocalyxin‐like protein 1 (PODXL)
primed stem cells
Online Access:https://doi.org/10.1002/advs.202205451

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