Connections between rheumatology and oncology – discussions based on a case report

Tumor necrosis factor (TNF) inhibitors are commonly utilized medications for the treatment of immune mediated conditions. Based on recent data from most registries there is no conclusive evidence for an increased risk of solid tumours or lymphoproliferative disease linked with biologic therapy, but...

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Bibliographic Details
Main Authors: Laura Groseanu, Mihaela Lebedenco, Anca Ursu, Carmen Petcu, Ruxandra Ionescu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2019-12-01
Series:Romanian Journal of Rheumatology
Subjects:
Online Access:https://rjr.com.ro/articles/2019.4/RJR_2019_4_Art-06.pdf
Description
Summary:Tumor necrosis factor (TNF) inhibitors are commonly utilized medications for the treatment of immune mediated conditions. Based on recent data from most registries there is no conclusive evidence for an increased risk of solid tumours or lymphoproliferative disease linked with biologic therapy, but on-going vigilance is required. We present a case of ankylosing spondylitis with extraarticular manifestations with a premalignant condition treated with TNF inhibitors, which developed a basal cell cancer, was switched on secukinumab and back again on antiTNF due to severe panuveitis.
ISSN:1843-0791
2069-6086