Connections between rheumatology and oncology – discussions based on a case report
Tumor necrosis factor (TNF) inhibitors are commonly utilized medications for the treatment of immune mediated conditions. Based on recent data from most registries there is no conclusive evidence for an increased risk of solid tumours or lymphoproliferative disease linked with biologic therapy, but...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Amaltea Medical Publishing House
2019-12-01
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| Series: | Romanian Journal of Rheumatology |
| Subjects: | |
| Online Access: | https://rjr.com.ro/articles/2019.4/RJR_2019_4_Art-06.pdf |
| _version_ | 1811335668790460416 |
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| author | Laura Groseanu Mihaela Lebedenco Anca Ursu Carmen Petcu Ruxandra Ionescu |
| author_facet | Laura Groseanu Mihaela Lebedenco Anca Ursu Carmen Petcu Ruxandra Ionescu |
| author_sort | Laura Groseanu |
| collection | DOAJ |
| description | Tumor necrosis factor (TNF) inhibitors are commonly utilized medications for the treatment of immune mediated conditions. Based on recent data from most registries there is no conclusive evidence for an increased risk of solid tumours or lymphoproliferative disease linked with biologic therapy, but on-going vigilance is required.
We present a case of ankylosing spondylitis with extraarticular manifestations with a premalignant condition treated with TNF inhibitors, which developed a basal cell cancer, was switched on secukinumab and back again on antiTNF due to severe panuveitis. |
| first_indexed | 2024-04-13T17:28:35Z |
| format | Article |
| id | doaj.art-3d6d70906c214852b99699b99beaaf47 |
| institution | Directory Open Access Journal |
| issn | 1843-0791 2069-6086 |
| language | English |
| last_indexed | 2024-04-13T17:28:35Z |
| publishDate | 2019-12-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Rheumatology |
| spelling | doaj.art-3d6d70906c214852b99699b99beaaf472022-12-22T02:37:40ZengAmaltea Medical Publishing HouseRomanian Journal of Rheumatology1843-07912069-60862019-12-0128416116610.37897/RJR.2019.4.6Connections between rheumatology and oncology – discussions based on a case reportLaura Groseanu0Mihaela Lebedenco1Anca Ursu2Carmen Petcu3Ruxandra Ionescu4“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Sfanta Maria” Clinical Hospital, Bucharest, Romania“Coltea” Clinical Hospital, Bucharest, Romania “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania“Sfanta Maria” Clinical Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Sfanta Maria” Clinical Hospital, Bucharest, RomaniaTumor necrosis factor (TNF) inhibitors are commonly utilized medications for the treatment of immune mediated conditions. Based on recent data from most registries there is no conclusive evidence for an increased risk of solid tumours or lymphoproliferative disease linked with biologic therapy, but on-going vigilance is required. We present a case of ankylosing spondylitis with extraarticular manifestations with a premalignant condition treated with TNF inhibitors, which developed a basal cell cancer, was switched on secukinumab and back again on antiTNF due to severe panuveitis. https://rjr.com.ro/articles/2019.4/RJR_2019_4_Art-06.pdfankylosing spondylitislymphoproliferative diseaseantitnfmalignancy |
| spellingShingle | Laura Groseanu Mihaela Lebedenco Anca Ursu Carmen Petcu Ruxandra Ionescu Connections between rheumatology and oncology – discussions based on a case report Romanian Journal of Rheumatology ankylosing spondylitis lymphoproliferative disease antitnf malignancy |
| title | Connections between rheumatology and oncology – discussions based on a case report |
| title_full | Connections between rheumatology and oncology – discussions based on a case report |
| title_fullStr | Connections between rheumatology and oncology – discussions based on a case report |
| title_full_unstemmed | Connections between rheumatology and oncology – discussions based on a case report |
| title_short | Connections between rheumatology and oncology – discussions based on a case report |
| title_sort | connections between rheumatology and oncology discussions based on a case report |
| topic | ankylosing spondylitis lymphoproliferative disease antitnf malignancy |
| url | https://rjr.com.ro/articles/2019.4/RJR_2019_4_Art-06.pdf |
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