Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional study
Abstract Previous studies showed that long interdialytic interval of chronic hemodialysis increased risk of sudden cardiac death compared to short interdialytic interval. Diabetes mellitus (DM) and autonomic dysfunction are the strong adverse predictors of survival in ESRD patients. We aimed to comp...
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| Format: | Article |
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Nature Portfolio
2021-10-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-00093-0 |
| _version_ | 1819044580110106624 |
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| author | Kajohnsak Noppakun Phasakorn Putchagarn Arintaya Phrommintikul Wanwarang Wongcharoen |
| author_facet | Kajohnsak Noppakun Phasakorn Putchagarn Arintaya Phrommintikul Wanwarang Wongcharoen |
| author_sort | Kajohnsak Noppakun |
| collection | DOAJ |
| description | Abstract Previous studies showed that long interdialytic interval of chronic hemodialysis increased risk of sudden cardiac death compared to short interdialytic interval. Diabetes mellitus (DM) and autonomic dysfunction are the strong adverse predictors of survival in ESRD patients. We aimed to compare autonomic function between long and short interdialytic interval of chronic hemodialysis in patients with and without DM. One-hundred sixty-three patients receiving chronic hemodialysis were enrolled. The electrocardiogram recording was performed twice in each patient during 4-h hemodialysis session after long and short interdialytic intervals to assess heart rate variability (HRV). Mean age was 61.4 ± 14.3 years. HRV parameters during hemodialysis did not differ between long and short interdialytic interval in overall population. Nevertheless, in 82 (50.3%) patients, SDNN (47.4 ± 23.8 vs. 43.4 ± 19.5 ms, P = 0.039), ASDNN (24.8 ± 14.3 vs. 22.7 ± 12.3 ms, P = 0.025), LF (8.4 ± 6.8 vs. 7.6 ± 6.6 ms2, P = 0.040) increased after long interdialytic interval. The greater change of SDNN, ASDNN, VLF and LF between long and short interdialytic intervals was noted in DM, compared to non-DM patients. We demonstrated that there was no difference of HRV parameters after short and long interdialytic interval. However, there was greater autonomic alteration observed in DM than non-DM patients between 2 interdialytic intervals. |
| first_indexed | 2024-12-21T10:14:56Z |
| format | Article |
| id | doaj.art-3d6e59b2ea174602bec6d004bbbd46e5 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-21T10:14:56Z |
| publishDate | 2021-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-3d6e59b2ea174602bec6d004bbbd46e52022-12-21T19:07:36ZengNature PortfolioScientific Reports2045-23222021-10-011111710.1038/s41598-021-00093-0Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional studyKajohnsak Noppakun0Phasakorn Putchagarn1Arintaya Phrommintikul2Wanwarang Wongcharoen3Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDivision of Cardiology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityAbstract Previous studies showed that long interdialytic interval of chronic hemodialysis increased risk of sudden cardiac death compared to short interdialytic interval. Diabetes mellitus (DM) and autonomic dysfunction are the strong adverse predictors of survival in ESRD patients. We aimed to compare autonomic function between long and short interdialytic interval of chronic hemodialysis in patients with and without DM. One-hundred sixty-three patients receiving chronic hemodialysis were enrolled. The electrocardiogram recording was performed twice in each patient during 4-h hemodialysis session after long and short interdialytic intervals to assess heart rate variability (HRV). Mean age was 61.4 ± 14.3 years. HRV parameters during hemodialysis did not differ between long and short interdialytic interval in overall population. Nevertheless, in 82 (50.3%) patients, SDNN (47.4 ± 23.8 vs. 43.4 ± 19.5 ms, P = 0.039), ASDNN (24.8 ± 14.3 vs. 22.7 ± 12.3 ms, P = 0.025), LF (8.4 ± 6.8 vs. 7.6 ± 6.6 ms2, P = 0.040) increased after long interdialytic interval. The greater change of SDNN, ASDNN, VLF and LF between long and short interdialytic intervals was noted in DM, compared to non-DM patients. We demonstrated that there was no difference of HRV parameters after short and long interdialytic interval. However, there was greater autonomic alteration observed in DM than non-DM patients between 2 interdialytic intervals.https://doi.org/10.1038/s41598-021-00093-0 |
| spellingShingle | Kajohnsak Noppakun Phasakorn Putchagarn Arintaya Phrommintikul Wanwarang Wongcharoen Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional study Scientific Reports |
| title | Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional study |
| title_full | Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional study |
| title_fullStr | Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional study |
| title_full_unstemmed | Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional study |
| title_short | Effects of interdialytic interval on heart rate variability in chronic hemodialysis patients: a cross-sectional study |
| title_sort | effects of interdialytic interval on heart rate variability in chronic hemodialysis patients a cross sectional study |
| url | https://doi.org/10.1038/s41598-021-00093-0 |
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