Plasma cell free DNA methylation markers for hepatocellular carcinoma surveillance in patients with cirrhosis: a case control study

Plasma cell free DNA methylation markers for hepatocellular carcinoma surveillance in patients with cirrhosis: a case control study

Abstract Background Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis, primarily due to failed early detection. HCC screening is recommended among individuals with cirrhosis using biannual abdominal ultrasound, for earlier tumor detection, administration of cura...

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Main Authors: Jörn Lewin, Denise Kottwitz, Johanna Aoyama, Theo deVos, Jorge Garces, Oliver Hasinger, Stefanie Kasielke, Florian Knaust, Preeti Rathi, Sebastian Rausch, Gunter Weiss, Alexander Zipprich, Edward Mena, Tse-Ling Fong
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Gastroenterology
Subjects:
Carcinoma
Hepatocellular
Liver cirrhosis
Early detection of cancer
Biomarker
Cell-free nucleic acids
Online Access:https://doi.org/10.1186/s12876-021-01714-8

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