Duodenal Hemorrhage from Pancreatic Cancer Infiltration Controlled through Combination Therapy with Gemcitabine and S-1

2.6% of pancreatic cancer patients have the primary manifestation of gastrointestinal bleeding. It is not feasible to stop the duodenal hemorrhage caused by the pancreatic cancer infiltration. A 43-year-old woman who was diagnosed as having pancreatic cancer with multiple hepatic metastases and duod...

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Main Authors: Ryoji Takada, Tatsuya Ioka, Hironari Sueyoshi, Nobuko Ishida, Takuo Yamai, Nobuyasu Fukutake, Reiko Ashida, Hiroyuki Uehara, Akemi Takenaka, Yasuhiko Tomita, Kazuhiro Katayama
Format: Article
Language:English
Published: Karger Publishers 2014-06-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:http://www.karger.com/Article/FullText/364819
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author Ryoji Takada
Tatsuya Ioka
Hironari Sueyoshi
Nobuko Ishida
Takuo Yamai
Nobuyasu Fukutake
Reiko Ashida
Hiroyuki Uehara
Akemi Takenaka
Yasuhiko Tomita
Kazuhiro Katayama
author_facet Ryoji Takada
Tatsuya Ioka
Hironari Sueyoshi
Nobuko Ishida
Takuo Yamai
Nobuyasu Fukutake
Reiko Ashida
Hiroyuki Uehara
Akemi Takenaka
Yasuhiko Tomita
Kazuhiro Katayama
author_sort Ryoji Takada
collection DOAJ
description 2.6% of pancreatic cancer patients have the primary manifestation of gastrointestinal bleeding. It is not feasible to stop the duodenal hemorrhage caused by the pancreatic cancer infiltration. A 43-year-old woman who was diagnosed as having pancreatic cancer with multiple hepatic metastases and duodenal infiltration was administered gemcitabine and S-1 combination therapy. During the chemotherapy, initially, bleeding occurred due to duodenal infiltration. However, we continued the chemotherapy and duodenal infiltration was markedly reduced in size and did not rebleed. Aggressive chemotherapy contributed to maintenance of performance status as well as improvement of quality of life for the patient.
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spelling doaj.art-3d6f71f045424d5f9caef08ce33f29542022-12-22T01:34:46ZengKarger PublishersCase Reports in Gastroenterology1662-06312014-06-018222122610.1159/000364819364819Duodenal Hemorrhage from Pancreatic Cancer Infiltration Controlled through Combination Therapy with Gemcitabine and S-1Ryoji TakadaTatsuya IokaHironari SueyoshiNobuko IshidaTakuo YamaiNobuyasu FukutakeReiko AshidaHiroyuki UeharaAkemi TakenakaYasuhiko TomitaKazuhiro Katayama2.6% of pancreatic cancer patients have the primary manifestation of gastrointestinal bleeding. It is not feasible to stop the duodenal hemorrhage caused by the pancreatic cancer infiltration. A 43-year-old woman who was diagnosed as having pancreatic cancer with multiple hepatic metastases and duodenal infiltration was administered gemcitabine and S-1 combination therapy. During the chemotherapy, initially, bleeding occurred due to duodenal infiltration. However, we continued the chemotherapy and duodenal infiltration was markedly reduced in size and did not rebleed. Aggressive chemotherapy contributed to maintenance of performance status as well as improvement of quality of life for the patient.http://www.karger.com/Article/FullText/364819ChemotherapyGastrointestinal bleedingPancreatic cancerDuodenal infiltration
spellingShingle Ryoji Takada
Tatsuya Ioka
Hironari Sueyoshi
Nobuko Ishida
Takuo Yamai
Nobuyasu Fukutake
Reiko Ashida
Hiroyuki Uehara
Akemi Takenaka
Yasuhiko Tomita
Kazuhiro Katayama
Duodenal Hemorrhage from Pancreatic Cancer Infiltration Controlled through Combination Therapy with Gemcitabine and S-1
Case Reports in Gastroenterology
Chemotherapy
Gastrointestinal bleeding
Pancreatic cancer
Duodenal infiltration
title Duodenal Hemorrhage from Pancreatic Cancer Infiltration Controlled through Combination Therapy with Gemcitabine and S-1
title_full Duodenal Hemorrhage from Pancreatic Cancer Infiltration Controlled through Combination Therapy with Gemcitabine and S-1
title_fullStr Duodenal Hemorrhage from Pancreatic Cancer Infiltration Controlled through Combination Therapy with Gemcitabine and S-1
title_full_unstemmed Duodenal Hemorrhage from Pancreatic Cancer Infiltration Controlled through Combination Therapy with Gemcitabine and S-1
title_short Duodenal Hemorrhage from Pancreatic Cancer Infiltration Controlled through Combination Therapy with Gemcitabine and S-1
title_sort duodenal hemorrhage from pancreatic cancer infiltration controlled through combination therapy with gemcitabine and s 1
topic Chemotherapy
Gastrointestinal bleeding
Pancreatic cancer
Duodenal infiltration
url http://www.karger.com/Article/FullText/364819
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