Trichothecenes in Cereal Grains – An Update
Trichothecenes are sesquiterpenoid mycotoxins produced by fungi from the order Hypocreales, including members of the <i>Fusarium</i> genus that infect cereal grain crops. Different trichothecene-producing <i>Fusarium</i> species and strains have different trichothecene chemot...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-10-01
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| Series: | Toxins |
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| Online Access: | https://www.mdpi.com/2072-6651/11/11/634 |
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| author | Nora A. Foroud Danica Baines Tatiana Y. Gagkaeva Nehal Thakor Ana Badea Barbara Steiner Maria Bürstmayr Hermann Bürstmayr |
| author_facet | Nora A. Foroud Danica Baines Tatiana Y. Gagkaeva Nehal Thakor Ana Badea Barbara Steiner Maria Bürstmayr Hermann Bürstmayr |
| author_sort | Nora A. Foroud |
| collection | DOAJ |
| description | Trichothecenes are sesquiterpenoid mycotoxins produced by fungi from the order Hypocreales, including members of the <i>Fusarium</i> genus that infect cereal grain crops. Different trichothecene-producing <i>Fusarium</i> species and strains have different trichothecene chemotypes belonging to the Type A and B class. These fungi cause a disease of small grain cereals, called Fusarium head blight, and their toxins contaminate host tissues. As potent inhibitors of eukaryotic protein synthesis, trichothecenes pose a health risk to human and animal consumers of infected cereal grains. In 2009, Foroud and Eudes published a review of trichothecenes in cereal grains for human consumption. As an update to this review, the work herein provides a comprehensive and multi-disciplinary review of the <i>Fusarium</i> trichothecenes covering topics in chemistry and biochemistry, pathogen biology, trichothecene toxicity, molecular mechanisms of resistance or detoxification, genetics of resistance and breeding strategies to reduce their contamination of wheat and barley. |
| first_indexed | 2024-04-11T22:03:01Z |
| format | Article |
| id | doaj.art-3d7385352973403dae425f329a440c1c |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-11T22:03:01Z |
| publishDate | 2019-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-3d7385352973403dae425f329a440c1c2022-12-22T04:00:51ZengMDPI AGToxins2072-66512019-10-01111163410.3390/toxins11110634toxins11110634Trichothecenes in Cereal Grains – An UpdateNora A. Foroud0Danica Baines1Tatiana Y. Gagkaeva2Nehal Thakor3Ana Badea4Barbara Steiner5Maria Bürstmayr6Hermann Bürstmayr7Lethbridge Research and Development Centre, Agriculture and Agri-Food Canada, Lethbridge, AB T1J 4B1, CanadaLethbridge Research and Development Centre, Agriculture and Agri-Food Canada, Lethbridge, AB T1J 4B1, CanadaLaboratory of Mycology and Phytopathology, All-Russian Institute of Plant Protection (VIZR), St. Petersburg, Pushkin 196608, RussiaDepartment of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, AB T1K 3M4, CanadaBrandon Research and Development Centre, Agriculture and Agri-Food Canada, Brandon, MB R7A 5Y3, CanadaDepartment of Agrobiotechnology (IFA-Tulln), Institute of Biotechnology in Plant Production, University of Natural Resources and Life Sciences, Vienna (BOKU), Tulln 3430, AustriaDepartment of Agrobiotechnology (IFA-Tulln), Institute of Biotechnology in Plant Production, University of Natural Resources and Life Sciences, Vienna (BOKU), Tulln 3430, AustriaDepartment of Agrobiotechnology (IFA-Tulln), Institute of Biotechnology in Plant Production, University of Natural Resources and Life Sciences, Vienna (BOKU), Tulln 3430, AustriaTrichothecenes are sesquiterpenoid mycotoxins produced by fungi from the order Hypocreales, including members of the <i>Fusarium</i> genus that infect cereal grain crops. Different trichothecene-producing <i>Fusarium</i> species and strains have different trichothecene chemotypes belonging to the Type A and B class. These fungi cause a disease of small grain cereals, called Fusarium head blight, and their toxins contaminate host tissues. As potent inhibitors of eukaryotic protein synthesis, trichothecenes pose a health risk to human and animal consumers of infected cereal grains. In 2009, Foroud and Eudes published a review of trichothecenes in cereal grains for human consumption. As an update to this review, the work herein provides a comprehensive and multi-disciplinary review of the <i>Fusarium</i> trichothecenes covering topics in chemistry and biochemistry, pathogen biology, trichothecene toxicity, molecular mechanisms of resistance or detoxification, genetics of resistance and breeding strategies to reduce their contamination of wheat and barley.https://www.mdpi.com/2072-6651/11/11/634deoxynivalenolt-2 toxin<i>fusarium</i>fusarium head blight (fhb)wheatbarleyresistance |
| spellingShingle | Nora A. Foroud Danica Baines Tatiana Y. Gagkaeva Nehal Thakor Ana Badea Barbara Steiner Maria Bürstmayr Hermann Bürstmayr Trichothecenes in Cereal Grains – An Update Toxins deoxynivalenol t-2 toxin <i>fusarium</i> fusarium head blight (fhb) wheat barley resistance |
| title | Trichothecenes in Cereal Grains – An Update |
| title_full | Trichothecenes in Cereal Grains – An Update |
| title_fullStr | Trichothecenes in Cereal Grains – An Update |
| title_full_unstemmed | Trichothecenes in Cereal Grains – An Update |
| title_short | Trichothecenes in Cereal Grains – An Update |
| title_sort | trichothecenes in cereal grains an update |
| topic | deoxynivalenol t-2 toxin <i>fusarium</i> fusarium head blight (fhb) wheat barley resistance |
| url | https://www.mdpi.com/2072-6651/11/11/634 |
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