Construction of nano slow-release systems for antibacterial active substances and its applications: A comprehensive review
At present, nano-carrier materials with antibacterial activity are of great significance. Due to the widespread resistance of many pathogenic microorganisms, it has seriously threatened human health. The natural antimicrobial substances extracted from fruits and vegetables can significantly improve...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-02-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2023.1109204/full |
| _version_ | 1797937954230894592 |
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| author | Jiayong Cao Jiayong Cao Mingkun Gao Jian Wang Yuan Liu Xuan Zhang Yi Ping Jia Liu Ge Chen Donghui Xu Xiaodong Huang Guangyang Liu |
| author_facet | Jiayong Cao Jiayong Cao Mingkun Gao Jian Wang Yuan Liu Xuan Zhang Yi Ping Jia Liu Ge Chen Donghui Xu Xiaodong Huang Guangyang Liu |
| author_sort | Jiayong Cao |
| collection | DOAJ |
| description | At present, nano-carrier materials with antibacterial activity are of great significance. Due to the widespread resistance of many pathogenic microorganisms, it has seriously threatened human health. The natural antimicrobial substances extracted from fruits and vegetables can significantly improve their stability combined with nano-carrier materials. The resistance of pathogenic microorganisms will be substantially reduced, greatly enhancing the effect of active antimicrobial substances. Nanotechnology has excellent research prospects in the food industry, antibacterial preservation, food additives, food packaging, and other fields. This paper introduces nano-carrier materials and preparation techniques for loading and encapsulating active antibacterial substances in detail by constructing a nano-release system for active antibacterial substances. The antibacterial effect can be achieved by protecting them from adverse external conditions and destroying the membrane of pathogenic microorganisms. The mechanism of the slow release of the bacteriostatic active substance is also described. The mechanism of carrier loading and release is mainly through non-covalent forces between the bacteriostatic active substance and the carrier material, such as hydrogen bonding, π-π stacking, van der Waals forces, electrostatic interactions, etc., as well as the loading and adsorption of the bacteriostatic active substance by the chemical assembly. Finally, its wide application in food and medicine is introduced. It is hoped to provide a theoretical basis and technical support for the efficient utilization and product development of bacteriostatic active substances. |
| first_indexed | 2024-04-10T18:53:27Z |
| format | Article |
| id | doaj.art-3d74e358fb8c4e6c81c47f0b0e62e35d |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-10T18:53:27Z |
| publishDate | 2023-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-3d74e358fb8c4e6c81c47f0b0e62e35d2023-02-01T05:07:31ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2023-02-011010.3389/fnut.2023.11092041109204Construction of nano slow-release systems for antibacterial active substances and its applications: A comprehensive reviewJiayong Cao0Jiayong Cao1Mingkun Gao2Jian Wang3Yuan Liu4Xuan Zhang5Yi Ping6Jia Liu7Ge Chen8Donghui Xu9Xiaodong Huang10Guangyang Liu11College of Agriculture and Forestry Science and Technology, Hebei North University, Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Zhangjiakou, ChinaState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing, ChinaState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing, ChinaCollege of Agriculture and Forestry Science and Technology, Hebei North University, Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Zhangjiakou, ChinaCollege of Agriculture and Forestry Science and Technology, Hebei North University, Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Zhangjiakou, ChinaCollege of Agriculture and Forestry Science and Technology, Hebei North University, Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Zhangjiakou, ChinaCollege of Horticulture, Northeast Agricultural University, Harbin, Heilongjiang, ChinaInternal Trade Food Science Research Institute Co., Ltd, Beijing, ChinaState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing, ChinaState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing, ChinaState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing, ChinaState Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing, ChinaAt present, nano-carrier materials with antibacterial activity are of great significance. Due to the widespread resistance of many pathogenic microorganisms, it has seriously threatened human health. The natural antimicrobial substances extracted from fruits and vegetables can significantly improve their stability combined with nano-carrier materials. The resistance of pathogenic microorganisms will be substantially reduced, greatly enhancing the effect of active antimicrobial substances. Nanotechnology has excellent research prospects in the food industry, antibacterial preservation, food additives, food packaging, and other fields. This paper introduces nano-carrier materials and preparation techniques for loading and encapsulating active antibacterial substances in detail by constructing a nano-release system for active antibacterial substances. The antibacterial effect can be achieved by protecting them from adverse external conditions and destroying the membrane of pathogenic microorganisms. The mechanism of the slow release of the bacteriostatic active substance is also described. The mechanism of carrier loading and release is mainly through non-covalent forces between the bacteriostatic active substance and the carrier material, such as hydrogen bonding, π-π stacking, van der Waals forces, electrostatic interactions, etc., as well as the loading and adsorption of the bacteriostatic active substance by the chemical assembly. Finally, its wide application in food and medicine is introduced. It is hoped to provide a theoretical basis and technical support for the efficient utilization and product development of bacteriostatic active substances.https://www.frontiersin.org/articles/10.3389/fnut.2023.1109204/fullnanocarriersencapsulation technologyassembly/release mechanismbacteriostaticantibacterial active substances |
| spellingShingle | Jiayong Cao Jiayong Cao Mingkun Gao Jian Wang Yuan Liu Xuan Zhang Yi Ping Jia Liu Ge Chen Donghui Xu Xiaodong Huang Guangyang Liu Construction of nano slow-release systems for antibacterial active substances and its applications: A comprehensive review Frontiers in Nutrition nanocarriers encapsulation technology assembly/release mechanism bacteriostatic antibacterial active substances |
| title | Construction of nano slow-release systems for antibacterial active substances and its applications: A comprehensive review |
| title_full | Construction of nano slow-release systems for antibacterial active substances and its applications: A comprehensive review |
| title_fullStr | Construction of nano slow-release systems for antibacterial active substances and its applications: A comprehensive review |
| title_full_unstemmed | Construction of nano slow-release systems for antibacterial active substances and its applications: A comprehensive review |
| title_short | Construction of nano slow-release systems for antibacterial active substances and its applications: A comprehensive review |
| title_sort | construction of nano slow release systems for antibacterial active substances and its applications a comprehensive review |
| topic | nanocarriers encapsulation technology assembly/release mechanism bacteriostatic antibacterial active substances |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2023.1109204/full |
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