Influence of methylation and demethylation on plant uptake of emerging contaminants
Contaminants of emerging concern (CECs) as well as their transformation products (TPs) are often found in treated wastewater and biosolids, raising concerns about their environmental risks. Small changes in chemical structure, such as the addition or loss of a methyl group, as the result of methylat...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Environment International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412022005396 |
| _version_ | 1797987256505466880 |
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| author | Yaxin Xiong Qingyang Shi Nathan D. Sy Nicole M. Dennis Daniel Schlenk Jay Gan |
| author_facet | Yaxin Xiong Qingyang Shi Nathan D. Sy Nicole M. Dennis Daniel Schlenk Jay Gan |
| author_sort | Yaxin Xiong |
| collection | DOAJ |
| description | Contaminants of emerging concern (CECs) as well as their transformation products (TPs) are often found in treated wastewater and biosolids, raising concerns about their environmental risks. Small changes in chemical structure, such as the addition or loss of a methyl group, as the result of methylation or demethylation reaction, may significantly alter a chemical’s physicochemical properties. In this study, we evaluated the difference in accumulation and translocation between four CECs and their respective methylated or demethylated derivatives in plant models. Suspended Arabidopsis thaliana cell culture and wheat seedlings were cultivated in nutrient solutions containing individual compounds at 1 mg/L. The methylated counterparts were generally more hydrophobic and showed comparative or greater accumulation in both plant models. For example, after 1 h incubation, methylparaben was found in A. thaliana cells at levels two orders of magnitude greater than demethylated methylparaben. In contrast, the demethylated counterparts, especially those with the addition of a hydroxyl group after demethylation, showed decreased plant uptake and limited translocation. For example, acetaminophen and demethylated naproxen were not detected in the shoots of wheat seedlings after hydroponic exposure. Results from this study suggest that common transformations such as methylation and demethylation may affect the environmental fate of CECs, and should be considered to obtain a more comprehensive understanding of risks of CECs in the environment. |
| first_indexed | 2024-04-11T07:45:57Z |
| format | Article |
| id | doaj.art-3d75312cc5c74a67a8ae4f5eac2a91ad |
| institution | Directory Open Access Journal |
| issn | 0160-4120 |
| language | English |
| last_indexed | 2024-04-11T07:45:57Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj.art-3d75312cc5c74a67a8ae4f5eac2a91ad2022-12-22T04:36:18ZengElsevierEnvironment International0160-41202022-12-01170107612Influence of methylation and demethylation on plant uptake of emerging contaminantsYaxin Xiong0Qingyang Shi1Nathan D. Sy2Nicole M. Dennis3Daniel Schlenk4Jay Gan5Department of Environmental Sciences, University of California, Riverside, CA 92521, USADepartment of Environmental Sciences, University of California, Riverside, CA 92521, USADepartment of Environmental Sciences, University of California, Riverside, CA 92521, USADepartment of Environmental Sciences, University of California, Riverside, CA 92521, USADepartment of Environmental Sciences, University of California, Riverside, CA 92521, USACorresponding author.; Department of Environmental Sciences, University of California, Riverside, CA 92521, USAContaminants of emerging concern (CECs) as well as their transformation products (TPs) are often found in treated wastewater and biosolids, raising concerns about their environmental risks. Small changes in chemical structure, such as the addition or loss of a methyl group, as the result of methylation or demethylation reaction, may significantly alter a chemical’s physicochemical properties. In this study, we evaluated the difference in accumulation and translocation between four CECs and their respective methylated or demethylated derivatives in plant models. Suspended Arabidopsis thaliana cell culture and wheat seedlings were cultivated in nutrient solutions containing individual compounds at 1 mg/L. The methylated counterparts were generally more hydrophobic and showed comparative or greater accumulation in both plant models. For example, after 1 h incubation, methylparaben was found in A. thaliana cells at levels two orders of magnitude greater than demethylated methylparaben. In contrast, the demethylated counterparts, especially those with the addition of a hydroxyl group after demethylation, showed decreased plant uptake and limited translocation. For example, acetaminophen and demethylated naproxen were not detected in the shoots of wheat seedlings after hydroponic exposure. Results from this study suggest that common transformations such as methylation and demethylation may affect the environmental fate of CECs, and should be considered to obtain a more comprehensive understanding of risks of CECs in the environment.http://www.sciencedirect.com/science/article/pii/S0160412022005396CECsPlant accumulationTransformation productsMethylated/demethylated derivatives |
| spellingShingle | Yaxin Xiong Qingyang Shi Nathan D. Sy Nicole M. Dennis Daniel Schlenk Jay Gan Influence of methylation and demethylation on plant uptake of emerging contaminants Environment International CECs Plant accumulation Transformation products Methylated/demethylated derivatives |
| title | Influence of methylation and demethylation on plant uptake of emerging contaminants |
| title_full | Influence of methylation and demethylation on plant uptake of emerging contaminants |
| title_fullStr | Influence of methylation and demethylation on plant uptake of emerging contaminants |
| title_full_unstemmed | Influence of methylation and demethylation on plant uptake of emerging contaminants |
| title_short | Influence of methylation and demethylation on plant uptake of emerging contaminants |
| title_sort | influence of methylation and demethylation on plant uptake of emerging contaminants |
| topic | CECs Plant accumulation Transformation products Methylated/demethylated derivatives |
| url | http://www.sciencedirect.com/science/article/pii/S0160412022005396 |
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