LU-177-PSMA TREATMENT FOR METASTATIC PROSTATE CANCER – CASE EXAMPLES OF MIRACLE RESPONSES
Prostate specific membrane antigen (PSMA) is expressed in unfavorable prostate cancer. PSMA is basis for new diagnostics and theranostics. 177Lu-PSMA radioligand therapy is mainly used for patients with endstage prostate cancer. This report describes two patients: one patient with a multiple recurre...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2018-03-01
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| Series: | Vestnik Urologii |
| Subjects: | |
| Online Access: | https://www.urovest.ru/jour/article/view/193 |
| _version_ | 1797272139939708928 |
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| author | K. Kairemo T. Joensuu |
| author_facet | K. Kairemo T. Joensuu |
| author_sort | K. Kairemo |
| collection | DOAJ |
| description | Prostate specific membrane antigen (PSMA) is expressed in unfavorable prostate cancer. PSMA is basis for new diagnostics and theranostics. 177Lu-PSMA radioligand therapy is mainly used for patients with endstage prostate cancer. This report describes two patients: one patient with a multiple recurrences and one with extensive metastastic disease during the first visit. Both these patients were treated with 177Lu-PSMA radioligand therapy with major response, i.e. complete response by imaging and substantial reduction of PSA. 177Lu-PSMA radioligand therapy gave only mild adverse effects. In conclusion, patients with metastatic prostate cancer, 177Lu-PSMA-617 radioligand therapy had an attractive therapeutic profile which had to be adjusted according to the patient´s need. |
| first_indexed | 2024-03-07T14:24:06Z |
| format | Article |
| id | doaj.art-3d7589dd40a34a24839fc71a7291a821 |
| institution | Directory Open Access Journal |
| issn | 2308-6424 |
| language | Russian |
| last_indexed | 2024-03-07T14:24:06Z |
| publishDate | 2018-03-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Vestnik Urologii |
| spelling | doaj.art-3d7589dd40a34a24839fc71a7291a8212024-03-06T08:56:03ZrusState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationVestnik Urologii2308-64242018-03-0161657510.21886/2308-6424-2018-6-1-65-75151LU-177-PSMA TREATMENT FOR METASTATIC PROSTATE CANCER – CASE EXAMPLES OF MIRACLE RESPONSESK. Kairemo0T. Joensuu1Docrates Cancer CenterDocrates Cancer CenterProstate specific membrane antigen (PSMA) is expressed in unfavorable prostate cancer. PSMA is basis for new diagnostics and theranostics. 177Lu-PSMA radioligand therapy is mainly used for patients with endstage prostate cancer. This report describes two patients: one patient with a multiple recurrences and one with extensive metastastic disease during the first visit. Both these patients were treated with 177Lu-PSMA radioligand therapy with major response, i.e. complete response by imaging and substantial reduction of PSA. 177Lu-PSMA radioligand therapy gave only mild adverse effects. In conclusion, patients with metastatic prostate cancer, 177Lu-PSMA-617 radioligand therapy had an attractive therapeutic profile which had to be adjusted according to the patient´s need.https://www.urovest.ru/jour/article/view/193metastatic prostate cancerprostate specific membrane antigenlu-177-psma |
| spellingShingle | K. Kairemo T. Joensuu LU-177-PSMA TREATMENT FOR METASTATIC PROSTATE CANCER – CASE EXAMPLES OF MIRACLE RESPONSES Vestnik Urologii metastatic prostate cancer prostate specific membrane antigen lu-177-psma |
| title | LU-177-PSMA TREATMENT FOR METASTATIC PROSTATE CANCER – CASE EXAMPLES OF MIRACLE RESPONSES |
| title_full | LU-177-PSMA TREATMENT FOR METASTATIC PROSTATE CANCER – CASE EXAMPLES OF MIRACLE RESPONSES |
| title_fullStr | LU-177-PSMA TREATMENT FOR METASTATIC PROSTATE CANCER – CASE EXAMPLES OF MIRACLE RESPONSES |
| title_full_unstemmed | LU-177-PSMA TREATMENT FOR METASTATIC PROSTATE CANCER – CASE EXAMPLES OF MIRACLE RESPONSES |
| title_short | LU-177-PSMA TREATMENT FOR METASTATIC PROSTATE CANCER – CASE EXAMPLES OF MIRACLE RESPONSES |
| title_sort | lu 177 psma treatment for metastatic prostate cancer case examples of miracle responses |
| topic | metastatic prostate cancer prostate specific membrane antigen lu-177-psma |
| url | https://www.urovest.ru/jour/article/view/193 |
| work_keys_str_mv | AT kkairemo lu177psmatreatmentformetastaticprostatecancercaseexamplesofmiracleresponses AT tjoensuu lu177psmatreatmentformetastaticprostatecancercaseexamplesofmiracleresponses |