Quantitative plasma proteomics identifies metallothioneins as a marker of acute-on-chronic liver failure associated acute kidney injury

Quantitative plasma proteomics identifies metallothioneins as a marker of acute-on-chronic liver failure associated acute kidney injury

BackgroundAcute kidney injury (AKI) considerably increases the risk of short-term mortality in acute-on-chronic liver failure (ACLF) but predicting AKI is not possible with existing tools. Our study aimed at de novo discovery of AKI biomarkers in ACLF.MethodsThis observational study had two phases-...

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Bibliographic Details
Main Authors: Pragyan Acharya, Rohini Saha, Javed Ahsan Quadri, Saba Sarwar, Maroof Ahmad Khan, Hem Chandra Sati, Nidhi Gauniyal, Ahmadullah Shariff, Shekhar Swaroop, Piyush Pathak, Shalimar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
ACLF
AKI
proteomics
biomarkers
metallothionein
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1041230/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1041230/full

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