Wearable motion sensors and digital biomarkers in stroke rehabilitation

We propose three novel digital biomarkers for the longitudinal performance monitoring and movement evaluation of hemiparetic patients, e.g. after stroke. We devised convergence points (CP) for the bilateral walking analysis based on gait parameters, e.g. stride duration using regression- modelling t...

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Main Authors: Derungs Adrian, Schuster-Amft Corina, Amft Oliver
Format: Article
Language:English
Published: De Gruyter 2020-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2020-3058
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author Derungs Adrian
Schuster-Amft Corina
Amft Oliver
author_facet Derungs Adrian
Schuster-Amft Corina
Amft Oliver
author_sort Derungs Adrian
collection DOAJ
description We propose three novel digital biomarkers for the longitudinal performance monitoring and movement evaluation of hemiparetic patients, e.g. after stroke. We devised convergence points (CP) for the bilateral walking analysis based on gait parameters, e.g. stride duration using regression- modelling to estimate similarity between body sides. The physical activity (PA) was devised to evaluate the energy expenditure of all extremities during training and free-living. The functional range of motion (fROM) is a digital biomarker to quantify the upper arm reaching ability, represented in 3D visualisations. In this work, we detail CP, PA, and fROM to derive rehabilitation insights for personalising therapies. We evaluated the proposed digital biomarkers in a clinical observation study with 11 patients after stroke during their rehabilitation including therapy and self-paced daily routines.
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spelling doaj.art-3d7b3411595b4642bbc1b35c8247abe72022-12-21T21:34:29ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042020-09-016322923210.1515/cdbme-2020-3058cdbme-2020-3058Wearable motion sensors and digital biomarkers in stroke rehabilitationDerungs Adrian0Schuster-Amft Corina1Amft Oliver2Chair of Digital Health, Friedrich-Alexander University, Erlangen-Nürnberg, Henkestr. 91, 91052Erlangen, GermanyResearch Department, Reha Rheinfelden,Rheinfelden, SwitzerlandChair of Digital Health, Friedrich-Alexander University, Erlangen-Nürnberg,Erlangen, GermanyWe propose three novel digital biomarkers for the longitudinal performance monitoring and movement evaluation of hemiparetic patients, e.g. after stroke. We devised convergence points (CP) for the bilateral walking analysis based on gait parameters, e.g. stride duration using regression- modelling to estimate similarity between body sides. The physical activity (PA) was devised to evaluate the energy expenditure of all extremities during training and free-living. The functional range of motion (fROM) is a digital biomarker to quantify the upper arm reaching ability, represented in 3D visualisations. In this work, we detail CP, PA, and fROM to derive rehabilitation insights for personalising therapies. We evaluated the proposed digital biomarkers in a clinical observation study with 11 patients after stroke during their rehabilitation including therapy and self-paced daily routines.https://doi.org/10.1515/cdbme-2020-3058inertial measurement unitstrokehemiparesisgait parametergait analysisdigital twinfree-living.
spellingShingle Derungs Adrian
Schuster-Amft Corina
Amft Oliver
Wearable motion sensors and digital biomarkers in stroke rehabilitation
Current Directions in Biomedical Engineering
inertial measurement unit
stroke
hemiparesis
gait parameter
gait analysis
digital twin
free-living.
title Wearable motion sensors and digital biomarkers in stroke rehabilitation
title_full Wearable motion sensors and digital biomarkers in stroke rehabilitation
title_fullStr Wearable motion sensors and digital biomarkers in stroke rehabilitation
title_full_unstemmed Wearable motion sensors and digital biomarkers in stroke rehabilitation
title_short Wearable motion sensors and digital biomarkers in stroke rehabilitation
title_sort wearable motion sensors and digital biomarkers in stroke rehabilitation
topic inertial measurement unit
stroke
hemiparesis
gait parameter
gait analysis
digital twin
free-living.
url https://doi.org/10.1515/cdbme-2020-3058
work_keys_str_mv AT derungsadrian wearablemotionsensorsanddigitalbiomarkersinstrokerehabilitation
AT schusteramftcorina wearablemotionsensorsanddigitalbiomarkersinstrokerehabilitation
AT amftoliver wearablemotionsensorsanddigitalbiomarkersinstrokerehabilitation