Modulating Glycoside Hydrolase Activity between Hydrolysis and Transfer Reactions Using an Evolutionary Approach

The proteins within the CAZy glycoside hydrolase family GH13 catalyze the hydrolysis of polysaccharides such as glycogen and starch. Many of these enzymes also perform transglycosylation in various degrees, ranging from secondary to predominant reactions. Identifying structural determinants associat...

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Bibliographic Details
Main Authors: Rodrigo A. Arreola-Barroso, Alexey Llopiz, Leticia Olvera, Gloria Saab-Rincón
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/21/6586