Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis

The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesi...

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Main Authors: Boni A. Afouda, Adam T. Lynch, Eduardo de Paiva Alves, Stefan Hoppler
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340918300088
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author Boni A. Afouda
Adam T. Lynch
Eduardo de Paiva Alves
Stefan Hoppler
author_facet Boni A. Afouda
Adam T. Lynch
Eduardo de Paiva Alves
Stefan Hoppler
author_sort Boni A. Afouda
collection DOAJ
description The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (Afouda et al., 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.
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spelling doaj.art-3d8a0c375d4448c5ba229419865deea82022-12-22T03:06:10ZengElsevierData in Brief2352-34092018-04-0117559563Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevisBoni A. Afouda0Adam T. Lynch1Eduardo de Paiva Alves2Stefan Hoppler3Institute of Medical Sciences, Foresterhill Health Campus, University of Aberdeen, Scotland, UKInstitute of Medical Sciences, Foresterhill Health Campus, University of Aberdeen, Scotland, UKCentre for Genome-Enabled Biology and Medicine, King's College Campus, University of Aberdeen, Scotland, UKInstitute of Medical Sciences, Foresterhill Health Campus, University of Aberdeen, Scotland, UK; Correspondence to: School of Medicine, Medical Sciences & Nutrition, Foresterhill Health Campus, Aberdeen AB 25 2ZD, Scotland, UK.The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in this article are related to the research article entitled “Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis” (Afouda et al., 2017) [1]. The present study identifies genes regulated by these individual cardiogenic GATA factors using genome-wide transcriptomics analysis. We have presented genes that are specifically regulated by each of them, as well those regulated by either of them. The gene ontology terms (GO) associated with the genes differentially affected are also presented. The data set will allow further investigations on the gene regulatory network downstream of individual cardiogenic GATA factors during cardiac muscle formation.http://www.sciencedirect.com/science/article/pii/S2352340918300088
spellingShingle Boni A. Afouda
Adam T. Lynch
Eduardo de Paiva Alves
Stefan Hoppler
Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
Data in Brief
title Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_full Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_fullStr Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_full_unstemmed Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_short Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
title_sort genome wide transcriptomics analysis of genes regulated by gata4 5 and 6 during cardiomyogenesis in xenopus laevis
url http://www.sciencedirect.com/science/article/pii/S2352340918300088
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AT eduardodepaivaalves genomewidetranscriptomicsanalysisofgenesregulatedbygata45and6duringcardiomyogenesisinxenopuslaevis
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