Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome
OBJECTIVE: To compare neurological symptoms and signs in HTLV-1 asymptomatic carriers and HTLV-1 patients with overactive bladder (OB) syndrome. METHODS: We studied 102 HTLV-1 positive individuals without HAM/TSP (HTLV-1 associated myelopathy/tropical spastic paraparesis) divided into two groups acc...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
2012-04-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000400005&lng=en&tlng=en |
| _version_ | 1818132828382035968 |
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| author | Davi Tanajura Costa André Luiz Muniz Alves dos Santos Néviton Matos de Castro Isadora Cristina de Siqueira Edgar Marcelino de Carvalho Filho Marshall Jay Glesby |
| author_facet | Davi Tanajura Costa André Luiz Muniz Alves dos Santos Néviton Matos de Castro Isadora Cristina de Siqueira Edgar Marcelino de Carvalho Filho Marshall Jay Glesby |
| author_sort | Davi Tanajura Costa |
| collection | DOAJ |
| description | OBJECTIVE: To compare neurological symptoms and signs in HTLV-1 asymptomatic carriers and HTLV-1 patients with overactive bladder (OB) syndrome. METHODS: We studied 102 HTLV-1 positive individuals without HAM/TSP (HTLV-1 associated myelopathy/tropical spastic paraparesis) divided into two groups according to the presence or absence of OB syndrome. Clinical interview, neurological exam and proviral load was performed in all patients. RESULTS AND CONCLUSIONS: Individuals with OB were more commonly female (84.3 vs. 60.8% of asymptomatics, p=0.01). The prevalence of neurological complaints was higher in OB group, especially hand or foot numbness and arm or leg weakness. There was no difference between the groups in neurological strength and reflexes. Weakness complaint remained strongly associated with OB in multivariate logistic regression analysis adjusting for sex and age [adjusted odds ratio and 95%CI 3.59 (1.45-8.88) in arms and 6.68 (2.63-16.93) in legs]. Proviral load was also different between the two groups with higher level on OB individuals. |
| first_indexed | 2024-12-11T08:43:02Z |
| format | Article |
| id | doaj.art-3d8ad92136964dbd97eb1f4333fa79f5 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-11T08:43:02Z |
| publishDate | 2012-04-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-3d8ad92136964dbd97eb1f4333fa79f52022-12-22T01:14:13ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272012-04-0170425225610.1590/S0004-282X2012000400005S0004-282X2012000400005Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndromeDavi Tanajura Costa0André Luiz Muniz Alves dos Santos1Néviton Matos de Castro2Isadora Cristina de Siqueira3Edgar Marcelino de Carvalho Filho4Marshall Jay Glesby5Universidade Federal da BahiaUniversidade Federal da BahiaUniversidade Federal da BahiaUniversidade Federal da BahiaUniversidade Federal da BahiaCornell UniversityOBJECTIVE: To compare neurological symptoms and signs in HTLV-1 asymptomatic carriers and HTLV-1 patients with overactive bladder (OB) syndrome. METHODS: We studied 102 HTLV-1 positive individuals without HAM/TSP (HTLV-1 associated myelopathy/tropical spastic paraparesis) divided into two groups according to the presence or absence of OB syndrome. Clinical interview, neurological exam and proviral load was performed in all patients. RESULTS AND CONCLUSIONS: Individuals with OB were more commonly female (84.3 vs. 60.8% of asymptomatics, p=0.01). The prevalence of neurological complaints was higher in OB group, especially hand or foot numbness and arm or leg weakness. There was no difference between the groups in neurological strength and reflexes. Weakness complaint remained strongly associated with OB in multivariate logistic regression analysis adjusting for sex and age [adjusted odds ratio and 95%CI 3.59 (1.45-8.88) in arms and 6.68 (2.63-16.93) in legs]. Proviral load was also different between the two groups with higher level on OB individuals.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000400005&lng=en&tlng=endoenças da medula espinalbexiga urinária neurogênicaparaparesia espástica tropicalmielite |
| spellingShingle | Davi Tanajura Costa André Luiz Muniz Alves dos Santos Néviton Matos de Castro Isadora Cristina de Siqueira Edgar Marcelino de Carvalho Filho Marshall Jay Glesby Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome Arquivos de Neuro-Psiquiatria doenças da medula espinal bexiga urinária neurogênica paraparesia espástica tropical mielite |
| title | Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome |
| title_full | Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome |
| title_fullStr | Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome |
| title_full_unstemmed | Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome |
| title_short | Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome |
| title_sort | neurological symptoms and signs in htlv 1 patients with overactive bladder syndrome |
| topic | doenças da medula espinal bexiga urinária neurogênica paraparesia espástica tropical mielite |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012000400005&lng=en&tlng=en |
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