Non-typhoid Salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with HIV and hepatitis C: A case report and literature review
Salmonella infections are responsible for a large burden of disease worldwide. Non-typhoidal Salmonella (NTS) species cause a myriad of disease manifestations, particularly amongst severely immunocompromised individuals. We present a rare case of endocarditis caused by the NTS species Salmonella Ent...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-01-01
|
| Series: | IDCases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250923000719 |
| _version_ | 1827931859665813504 |
|---|---|
| author | Lyle Murray Michelle Venter Michel Le Grange Ruchika Meel |
| author_facet | Lyle Murray Michelle Venter Michel Le Grange Ruchika Meel |
| author_sort | Lyle Murray |
| collection | DOAJ |
| description | Salmonella infections are responsible for a large burden of disease worldwide. Non-typhoidal Salmonella (NTS) species cause a myriad of disease manifestations, particularly amongst severely immunocompromised individuals. We present a rare case of endocarditis caused by the NTS species Salmonella Enteritidis in an individual living with HIV and hepatitis C. In this case, endocarditis was complicated by embolization and acute arterial occlusion of the left arm, as well as mitral valve perforation resulting in cardiac failure. A review of the available literature shows few cases of NTS causing endocarditis in people living with HIV, with the earliest reported case in 1983. Our case demonstrates the potential complications of NTS endocarditis and highlights the importance of evaluating patients with NTS-associated blood stream infection for cardiovascular involvement. Prompt surgical intervention in addition to appropriate antimicrobial therapy is essential to reduce the high morbidity and mortality associated with NTS endocarditis. |
| first_indexed | 2024-03-13T06:58:49Z |
| format | Article |
| id | doaj.art-3d8e4571282043fbbbdc01198b4bcf9e |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-03-13T06:58:49Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-3d8e4571282043fbbbdc01198b4bcf9e2023-06-07T04:48:08ZengElsevierIDCases2214-25092023-01-0132e01747Non-typhoid Salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with HIV and hepatitis C: A case report and literature reviewLyle Murray0Michelle Venter1Michel Le Grange2Ruchika Meel3Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Division of Infectious Diseases, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Corresponding author at: Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Division of Infectious Diseases, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaDepartment of Clinical Microbiology and Infectious Diseases, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and National Health Laboratory Service, Johannesburg, South AfricaDepartment of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Division of Cardiology, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaSalmonella infections are responsible for a large burden of disease worldwide. Non-typhoidal Salmonella (NTS) species cause a myriad of disease manifestations, particularly amongst severely immunocompromised individuals. We present a rare case of endocarditis caused by the NTS species Salmonella Enteritidis in an individual living with HIV and hepatitis C. In this case, endocarditis was complicated by embolization and acute arterial occlusion of the left arm, as well as mitral valve perforation resulting in cardiac failure. A review of the available literature shows few cases of NTS causing endocarditis in people living with HIV, with the earliest reported case in 1983. Our case demonstrates the potential complications of NTS endocarditis and highlights the importance of evaluating patients with NTS-associated blood stream infection for cardiovascular involvement. Prompt surgical intervention in addition to appropriate antimicrobial therapy is essential to reduce the high morbidity and mortality associated with NTS endocarditis.http://www.sciencedirect.com/science/article/pii/S2214250923000719EndocarditisHepatitis CHIVSalmonellaNon-typhoidal SalmonellaSalmonella Enteritidis |
| spellingShingle | Lyle Murray Michelle Venter Michel Le Grange Ruchika Meel Non-typhoid Salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with HIV and hepatitis C: A case report and literature review IDCases Endocarditis Hepatitis C HIV Salmonella Non-typhoidal Salmonella Salmonella Enteritidis |
| title | Non-typhoid Salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with HIV and hepatitis C: A case report and literature review |
| title_full | Non-typhoid Salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with HIV and hepatitis C: A case report and literature review |
| title_fullStr | Non-typhoid Salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with HIV and hepatitis C: A case report and literature review |
| title_full_unstemmed | Non-typhoid Salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with HIV and hepatitis C: A case report and literature review |
| title_short | Non-typhoid Salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with HIV and hepatitis C: A case report and literature review |
| title_sort | non typhoid salmonella endocarditis complicated by cardiac failure and acute limb ischaemia in a person living with hiv and hepatitis c a case report and literature review |
| topic | Endocarditis Hepatitis C HIV Salmonella Non-typhoidal Salmonella Salmonella Enteritidis |
| url | http://www.sciencedirect.com/science/article/pii/S2214250923000719 |
| work_keys_str_mv | AT lylemurray nontyphoidsalmonellaendocarditiscomplicatedbycardiacfailureandacutelimbischaemiainapersonlivingwithhivandhepatitiscacasereportandliteraturereview AT michelleventer nontyphoidsalmonellaendocarditiscomplicatedbycardiacfailureandacutelimbischaemiainapersonlivingwithhivandhepatitiscacasereportandliteraturereview AT michellegrange nontyphoidsalmonellaendocarditiscomplicatedbycardiacfailureandacutelimbischaemiainapersonlivingwithhivandhepatitiscacasereportandliteraturereview AT ruchikameel nontyphoidsalmonellaendocarditiscomplicatedbycardiacfailureandacutelimbischaemiainapersonlivingwithhivandhepatitiscacasereportandliteraturereview |