Alternative therapy interaction with warfarin: what doctors should know

Warfarin effectiveness and safety is substantially affected by concurrent therapy. This paper reviews the main mechanisms of warfarin interactions with other agents, which underlie adverse effect development: platelet dysfunction, gastro-intestinal effects, suppressed intestinal synthesis of vitamin...

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Main Authors: T. B. Kozlova, T. V. Taratuta, M. B. Aksenova, T. V. Khlevchuk
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2010-06-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2094
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author T. B. Kozlova
T. V. Taratuta
M. B. Aksenova
T. V. Khlevchuk
author_facet T. B. Kozlova
T. V. Taratuta
M. B. Aksenova
T. V. Khlevchuk
author_sort T. B. Kozlova
collection DOAJ
description Warfarin effectiveness and safety is substantially affected by concurrent therapy. This paper reviews the main mechanisms of warfarin interactions with other agents, which underlie adverse effect development: platelet dysfunction, gastro-intestinal effects, suppressed intestinal synthesis of vitamin K, disturbed warfarin metabolism, or disrupted vitamin K cycle. The main medication groups, affecting warfarin effectiveness and safety, are presented. The effects of foods, supplements, and herbal medications on anticoagulant effect of warfarin are discussed.
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spelling doaj.art-3d8f4eaffb914e3dbfbfcff9ee84e8fd2023-03-13T07:23:18Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252010-06-01931061101805Alternative therapy interaction with warfarin: what doctors should knowT. B. Kozlova0T. V. Taratuta1M. B. Aksenova2T. V. Khlevchuk3Московская медицинская академия им. И. М. Сеченова. МоскваМосковская медицинская академия им. И. М. Сеченова. МоскваМосковская медицинская академия им. И. М. Сеченова. МоскваМосковская медицинская академия им. И. М. Сеченова. МоскваWarfarin effectiveness and safety is substantially affected by concurrent therapy. This paper reviews the main mechanisms of warfarin interactions with other agents, which underlie adverse effect development: platelet dysfunction, gastro-intestinal effects, suppressed intestinal synthesis of vitamin K, disturbed warfarin metabolism, or disrupted vitamin K cycle. The main medication groups, affecting warfarin effectiveness and safety, are presented. The effects of foods, supplements, and herbal medications on anticoagulant effect of warfarin are discussed.https://cardiovascular.elpub.ru/jour/article/view/2094варфаринсопутствующая терапиявзаимодействие с пищевыми и растительными продуктамиконтроль мно
spellingShingle T. B. Kozlova
T. V. Taratuta
M. B. Aksenova
T. V. Khlevchuk
Alternative therapy interaction with warfarin: what doctors should know
Кардиоваскулярная терапия и профилактика
варфарин
сопутствующая терапия
взаимодействие с пищевыми и растительными продуктами
контроль мно
title Alternative therapy interaction with warfarin: what doctors should know
title_full Alternative therapy interaction with warfarin: what doctors should know
title_fullStr Alternative therapy interaction with warfarin: what doctors should know
title_full_unstemmed Alternative therapy interaction with warfarin: what doctors should know
title_short Alternative therapy interaction with warfarin: what doctors should know
title_sort alternative therapy interaction with warfarin what doctors should know
topic варфарин
сопутствующая терапия
взаимодействие с пищевыми и растительными продуктами
контроль мно
url https://cardiovascular.elpub.ru/jour/article/view/2094
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AT tvkhlevchuk alternativetherapyinteractionwithwarfarinwhatdoctorsshouldknow