Impairment of rigidity sensing caused by mutant TP53 gain of function in osteosarcoma
Abstract Osteosarcoma (OS) is the most common primary malignant pediatric bone tumor and is characterized by high heterogeneity. Studies have revealed a wide range of phenotypic differences among OS cell lines in terms of their in vivo tumorigenicity and in vitro colony-forming abilities. However, t...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2023-05-01
|
| Series: | Bone Research |
| Online Access: | https://doi.org/10.1038/s41413-023-00265-w |