Toll-like receptor 5 and Toll-like receptor 9 single nucleotide polymorphisms and risk of systemic lupus erythematosus and nephritis in Egyptian patients

Toll-like receptor 5 and Toll-like receptor 9 single nucleotide polymorphisms and risk of systemic lupus erythematosus and nephritis in Egyptian patients

Abstract Background Toll-like (TLRs) play a crucial role in both adaptive and innate immunity. The aim of the present study was to assess the association of TLR5-rs5744168, TLR9-rs187084, and TLR9-rs352140 single nucleotide polymorphisms (SNPs) with susceptibility to systemic lupus erythematosus (SL...

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Main Authors: Ola Mohammad Gharbia, Sherine Abdel Rahman Bassiouni, Maysaa El Sayed Zaki, Shimaa Mohsen El-Beah, Manal Mohamed El-Desoky, Eman Adel Elmansoury, Mostafa Abdelsalam
Format: Article
Language:English
Published: SpringerOpen 2021-12-01
Series:Egyptian Rheumatology and Rehabilitation
Subjects:
Toll-like receptor
Systemic lupus erythematosus
Lupus nephritis
Single nucleotide polymorphisms
Online Access:https://doi.org/10.1186/s43166-021-00093-y

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