Is It Possible to Find Needles in a Haystack? Meta-Analysis of 1000+ MS/MS Files Provided by the Russian Proteomic Consortium for Mining Missing Proteins

Is It Possible to Find Needles in a Haystack? Meta-Analysis of 1000+ MS/MS Files Provided by the Russian Proteomic Consortium for Mining Missing Proteins

Despite direct or indirect efforts of the proteomic community, the fraction of blind spots on the protein map is still significant. Almost 11% of human genes encode missing proteins; the existence of which proteins is still in doubt. Apparently, proteomics has reached a stage when more attention and...

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Bibliographic Details
Main Authors: Ekaterina Poverennaya, Olga Kiseleva, Ekaterina Ilgisonis, Svetlana Novikova, Arthur Kopylov, Yuri Ivanov, Alexei Kononikhin, Mikhail Gorshkov, Nikolay Kushlinskii, Alexander Archakov, Elena Ponomarenko
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Proteomes
Subjects:
human proteome
missing proteins
uncertain proteins
neXtProt
proteotypic peptide
mass spectrometry
Online Access:https://www.mdpi.com/2227-7382/8/2/12

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