Ethyl 3-amino-4-(4-chlorophenyl)-2-[(4-methoxyphenyl)carbamoyl]-6-phenylthieno[2,3-b]pyridine-5-carboxylate

Ethyl 3-amino-4-(4-chlorophenyl)-2-[(4-methoxyphenyl)carbamoyl]-6-phenylthieno[2,3-b]pyridine-5-carboxylate

The conformation of the title molecule, C30H24ClN3O4S, is partially determined by an intramolecular N—H...O hydrogen bond, forming an S(6) loop, and an N—H...π interaction involving the centroid of the 4-chlorophenyl ring. The thienopyridine bicyclic system is almost planar with an r.m.s. deviation...

Full description

Bibliographic Details
Main Authors:	Etify A. Bakhite, Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Elham A. Al-Taifi
Format:	Article
Language:	English
Published:	International Union of Crystallography 2016-04-01
Series:	IUCrData
Subjects:	crystal structure thienopyridines 3-aminothiophene ethyl thieno[2,3-b]pyridine-5-carboxylate hydrogen bonding
Online Access:	http://scripts.iucr.org/cgi-bin/paper?S241431461600657X

Similar Items

5-Acetyl-3-amino-4-(4-methoxyphenyl)-6-methylthieno[2,3-b]pyridine-2-carbonitrile
by: Shaaban K. Mohamed, et al.
Published: (2017-12-01)

Ethyl 3-amino-2-carbamoyl-4-(4-methoxyphenyl)-6-methylthieno[2,3-b]pyridine-5-carboxylate dimethyl sulfoxide monosolvate
by: Etify A. Bakhite, et al.
Published: (2016-09-01)

Ethyl 3-amino-2-cyano-4-(4-methoxyphenyl)-6- methylthieno[2,3-b]pyridine-5-carboxylate
by: Etify A. Bakhite, et al.
Published: (2017-11-01)

Diethyl 3-amino-6-methyl-4-[(E)-2-phenylethenyl]thieno[2,3-b]pyridine-2,5-dicarboxylate
by: Joel T. Mague, et al.
Published: (2016-02-01)

The synthesis and application of 3-arylazo-4-phenylthieno[2,3-c]isothiazole and ethyl 3-arylazo-4-phenylthieno[2,3-c]isothiazole-5-carboxylate
by: G. G. PAWAR, et al.
Published: (2005-06-01)

The synthesis and application of 3-arylazo-4-phenylthieno[2, 3-c]isothiazole and ethyl 3-arylazo-4-phenylthieno[2, 3-c]isothiazole- 5-carboxylate
by: Pawar G.G., et al.
Published: (2005-01-01)

Ethyl {[5-acetyl-3-cyano-4-(4-methoxyphenyl)-6-methylpyridin-2-yl]sulfanyl}acetate
by: Elham A. Al-Taifi, et al.
Published: (2016-11-01)

Crystal structure of (4-methoxyphenyl)[(4-methoxyphenyl)phosphonato]dioxidophosphate(1−) 2-amino-6-benzyl-3-ethoxycarbonyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-ium
by: Joel T. Mague, et al.
Published: (2015-12-01)

Synthesis of some new Thieno[2,3-b]pyridines, Pyrimidino[4',5':4,5]thieno[2,3-b]pyridine and Pyridines Incorporating 5-Bromobenzofuran-2-yl Moiety
by: Nadia Abdelhamed Abdelriheem, et al.
Published: (2015-01-01)

Evaluation of Neurotropic Activity and Molecular Docking Study of New Derivatives of pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]thieno[3,2-<i>d</i>]pyrimidines on the Basis of pyrano[3,4-<i>c</i>]pyridines
by: Shushanik Sh. Dashyan, et al.
Published: (2022-05-01)

Ethyl 4-(4-chlorophenyl)-5-cyano-2-methyl-6-sulfanylidene-1,6-dihydropyridine-3-carboxylate
by: Joel T. Mague, et al.
Published: (2016-04-01)

Structure–Activity Relationship of <i>N</i>-Phenylthieno[2,3-<i>b</i>]pyridine-2-carboxamide Derivatives Designed as Forkhead Box M1 Inhibitors: The Effect of Electron-Withdrawing and Donating Substituents on the Phenyl Ring
by: César Sebastian Huerta-García, et al.
Published: (2022-02-01)

Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetic acid ethyl ester
by: Elham A. Al-Taifi, et al.
Published: (2022-02-01)

Overview on the chemistry of 1-(4-substituted aminophenyl) ethanones Part(I)
by: MOUSTAFA Gouda, et al.
Published: (2020-12-01)

4-[(4-Chlorophenyl)carbamoyl]butanoic Acid
by: Bibi Hanifa, et al.
Published: (2021-05-01)

Ethyl 3-({[(4-methylphenyl)carbamoyl]methyl}sulfanyl)-5,6-diphenylpyridazine-4-carboxylate
by: Joel T. Mague, et al.
Published: (2016-03-01)

Empirical determination of the degree of analgesic activity of some new 3-aminothieno[2,3-b]pyridines and 1,4-dihydropyridines based on a complex criterion
by: Igor V. Bibik, et al.
Published: (2023-05-01)

Synthesis and Cytotoxicity of Thieno[2,3-b]Pyridine Derivatives Toward Sensitive and Multidrug-Resistant Leukemia Cells
by: Salah A. Al-Trawneh, et al.
Published: (2021-06-01)

Crystal Structure and Computational Study on Methyl-3-Aminothiophene-2-Carboxylate
by: Yaping Tao, et al.
Published: (2020-01-01)

Crystal structure of ethyl (E)-4-(4-chlorophenyl)-4-methoxy-2-oxobut-3-enoate
by: Darlene Correia Flores, et al.
Published: (2014-09-01)

Methyl 2-{[(6S*,7R*,8S*)-7-acetyl-8-(4-chlorophenyl)-4-cyano-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetate
by: Joel T. Mague, et al.
Published: (2017-06-01)

Synthesis of 1H-pyrazolo[3,4-b]pyridine analogues
by: Yen Nguyen, et al.
Published: (2025-03-01)

6-Bromo-2-(4-chlorophenyl)-3-methyl-3H-imidazo[4,5-b]pyridine
by: Selma Bourichi, et al.
Published: (2016-05-01)

1-[({5-[(4-Methylphenoxy)methyl]-4-phenyl-4H-1,2,4-triazol-3-yl}sulfanyl)methyl]-1H-benzo[d][1,2,3]triazole
by: Shaaban K. Mohamed, et al.
Published: (2016-11-01)

Disruption of Crystal Packing in Thieno[2,3-<i>b</i>]pyridines Improves Anti-Proliferative Activity
by: Natalie A. Haverkate, et al.
Published: (2022-01-01)

7-Acetyl-8-(4-chlorophenyl)-3-ethylsulfanyl-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile
by: Joel T. Mague, et al.
Published: (2017-03-01)

Crystal structure of 4-(1H-indol-3-yl)-2-(4-methoxyphenyl)-6-phenylpyridine-3-carbonitrile
by: R. Vishnupriya, et al.
Published: (2014-10-01)

Synthesis of 1,3,4-Oxadiazole Derivatives from Ethyl-2-Piperidone-3-Carboxylate
by: M. A. Sheat, et al.
Published: (2012-03-01)

Crystal structure of 4,6-diamino-2-(methylsulfanyl)pyridine-3-carbonitrile
by: Shaaban K. Mohamed, et al.
Published: (2015-03-01)

Facile Synthesis of Some Novel Pyrido[3', 2': 4, 5]thieno[2,3-b][1,4]thiazine-8-carboxylic Acids
by: Salim S Sabri, et al.
Published: (2007-03-01)

5-Methyl-1-phenyl-3-(thieno[2,3-<i>d</i>]pyrimidin-4-yl)chromeno[4,3-<i>d</i>]pyrazolo[3,4-<i>b</i>]pyridin-6(3<i>H</i>)-one
by: Xuelian Yin, et al.
Published: (2022-10-01)

Synthesis and Antimicrobial Evaluation of 2-(6-Imidazo[1,2-<i>a</i>]pyridin-2-yl-5-methyl-2,4-dioxo-3-phenyl-3,4-dihydrothieno[2,3-<i>d</i>]pyrimidin-1(2<i>H</i>)-yl)-<i>N</i>-arylacetamide Derivatives
by: Sergiy V. Vlasov, et al.
Published: (2022-02-01)

Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-8-(4-chlorophenyl)-4-cyano-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}-N-(4-chlorophenyl)acetamide
by: Mehmet Akkurt, et al.
Published: (2021-05-01)

Novel quinolines carrying pyridine, thienopyridine, isoquinoline, thiazolidine, thiazole and thiophene moieties as potential anticancer agents
by: Ghorab Mostafa M., et al.
Published: (2016-06-01)

Visible light-promoted synthesis of 2-aryl-(3-organoselanyl)thieno[2,3-b]pyridines
by: Ricardo Hellwig Bartz, et al.
Published: (2022-04-01)

3-Phenoxymethyl-6-phenyl-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
by: Shaaban K. Mohamed, et al.
Published: (2016-04-01)

4-Arylthieno[2,3-<i>b</i>]pyridine-2-carboxamides Are a New Class of Antiplasmodial Agents
by: Sandra I. Schweda, et al.
Published: (2020-07-01)

Molecular modelling insights into a physiologically favourable approach to eicosanoid biosynthesis inhibition through novel thieno[2,3-b]pyridine derivatives
by: Mosaad S. Mohamed, et al.
Published: (2018-01-01)

2-[(2-Hydroxy-benzylidene)-amino]-5,6-dihydro-4H-cyclopenta [b] Thiophene-3-carboxylic Acid Methyl Ester
by: Abdullah Mohamed Asiri
Published: (2007-05-01)

Synthesis and structural characterization of new ladder-like organostannoxanes derived from carboxylic acid derivatives: [C5H4N(p-CO2)]2[Bu2Sn]4(μ3-O)2(μ2-OH)2, [Ph2CHCO2]4[Bu2Sn]4(μ3-O)2, and [(p-NH2)-C6H4-CO2]2[Bu2Sn]4(μ3-O)2(μ2-OH)2
by: Diop Tidiane, et al.
Published: (2022-05-01)