The First Dimeric Derivatives of the Glycopeptide Antibiotic Teicoplanin

The First Dimeric Derivatives of the Glycopeptide Antibiotic Teicoplanin

Various dimeric derivatives of the glycopeptide antibiotic teicoplanin were prepared with the aim of increasing the activity of the parent compound against glycopeptide-resistant bacteria, primarily vancomycin-resistant enterococci. Starting from teicoplanin, four covalent dimers were prepared in tw...

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Bibliographic Details
Main Authors: Ilona Bereczki, Zsolt Szűcs, Gyula Batta, Tamás Milán Nagy, Eszter Ostorházi, Katalin E. Kövér, Anikó Borbás, Pál Herczegh
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceuticals
Subjects:
teicoplanin
pseudoaglycone
synthesis
dimer
Co(III) complex
DOSY NMR
Online Access:https://www.mdpi.com/1424-8247/15/1/77

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