Repurposing of monacolin K decorated BN nanoparticle on inhibition of HMG-CoA reductase: In silico approach

Repurposing of monacolin K decorated BN nanoparticle on inhibition of HMG-CoA reductase: In silico approach

To identify a novel inhibitor of 3‑hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the current perspective has shifted toward a B12N12 nanocage that also has cardioprotective properties. Therefore, this study identified the bioactive complexes derived from monacolin K and BN nanoparticle a...

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Bibliographic Details
Main Authors:	Vahid Khori, Mahdi Zahedi, Hassan Mirzaei, Ali Jabbari, seyedbabak Mojaveraghili, Seyed Ghadir Hosseini
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Series:	Chemical Physics Impact
Subjects:	Monacolin K B12N12 Cardiovascular diseases Molecular docking simulation ADMET
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667022423002232

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