Synergistic anti-proliferative activity of JQ1 and GSK2801 in triple-negative breast cancer

Synergistic anti-proliferative activity of JQ1 and GSK2801 in triple-negative breast cancer

Abstract Background Triple-negative breast cancer (TNBC) constitutes 10–20% of breast cancers and is challenging to treat due to a lack of effective targeted therapies. Previous studies in TNBC cell lines showed in vitro growth inhibition when JQ1 or GSK2801 were administered alone, and enhanced act...

Full description

Bibliographic Details
Main Authors: Nanda Kumar Yellapu, Thuc Ly, Mihaela E. Sardiu, Dong Pei, Danny R. Welch, Jeffery A. Thompson, Devin C. Koestler
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Cancer
Subjects:
Breast cancer
RNASeq
Differential expression analysis
Drug resistance
Expression studies
MTT assay
Online Access:https://doi.org/10.1186/s12885-022-09690-2

Internet

https://doi.org/10.1186/s12885-022-09690-2

Similar Items