Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

The fibroblast growth factor receptor 4 (FGFR4) is overexpressed in rhabdomyosarcoma (RMS) and represents a promising target for treatments based on specific and efficient antibodies. Despite progress, there is an urgent need for targeted treatment options to improve survival rates, and to limit lon...

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Bibliographic Details
Main Authors: Nagjie Alijaj, Sandrine Moutel, Zelia L. Gouveia, Maxim Gray, Maurizio Roveri, Dzhangar Dzhumashev, Florian Weber, Gianmarco Meier, Paola Luciani, Jochen K. Rössler, Beat W. Schäfer, Franck Perez, Michele Bernasconi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
rhabdomyosarcoma
FGFR4
single-domain antibody
targeted liposomes
CAR T cells
Online Access:https://www.mdpi.com/2072-6694/12/11/3313

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