Paraspinal muscle characteristics on MRI in degenerative lumbar spine with normal bone density, osteopenia and osteoporosis: a case-control study
Abstract Background To investigate the difference of paraspinal muscles in patients with normal bone density, osteopenia and osteoporosis. Methods Patients undergoing surgery for lumbar spinal stenosis were included. Thirty-eight patients with osteoporosis were matched to patients with osteopenia an...
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| Format: | Article |
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BMC
2022-01-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-022-05036-y |
| _version_ | 1818332925922377728 |
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| author | Gengyu Han Da Zou Zexiang Liu Siyu Zhou Wei Li Chunjie Gong Zhuoran Sun Weishi Li |
| author_facet | Gengyu Han Da Zou Zexiang Liu Siyu Zhou Wei Li Chunjie Gong Zhuoran Sun Weishi Li |
| author_sort | Gengyu Han |
| collection | DOAJ |
| description | Abstract Background To investigate the difference of paraspinal muscles in patients with normal bone density, osteopenia and osteoporosis. Methods Patients undergoing surgery for lumbar spinal stenosis were included. Thirty-eight patients with osteoporosis were matched to patients with osteopenia and patients with normal bone density in a 1:1 manner according to WHO criteria. Dual-energy X-ray absorptiometry (DXA) scans and lumbar CT were performed preoperatively to measure the BMD of lumbar, femur and hip and HU values of L1-L4 respectively. The relative total cross-sectional area (rTCSA) and fat infiltration (FI) of multifidus (MF) and erector spinae (ES), and the relative functional CSA (rFCSA) of psoas major (PS) were measured at L4–5 and L5-S level on preoperative MRI. Results Osteoporotic patients showed lower BMI, higher MF FI and higher ES FI when compared with normal bone density group (25.57 ± 3.71 vs 27.46 ± 3.11; 0.38 ± 0.1 vs 0.32 ± 0.08; 0.33 ± 0.1 vs 0.28 ± 0.08; all adjusted p < 0.05). Both the MF FI and ES FI were significantly correlated with lumbar T-score (r = − 0.223, p < 0.05; r = − 0.208, p < 0.05) and the averaged lumbar HU value (r = − 0.305, p < 0.01; r = − 0.239, p < 0.05). Conclusions Osteoporosis and paraspinal muscle degeneration might interact with each other and coexist in patients with degenerative lumbar diseases. It is recommended that the paraspinal muscle degeneration should be considered simultaneously when finding a patient with low bone mass before surgery. |
| first_indexed | 2024-12-13T13:43:30Z |
| format | Article |
| id | doaj.art-3dab4ef6217f4e5c8890d4f38d79069c |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-13T13:43:30Z |
| publishDate | 2022-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-3dab4ef6217f4e5c8890d4f38d79069c2022-12-21T23:43:31ZengBMCBMC Musculoskeletal Disorders1471-24742022-01-012311710.1186/s12891-022-05036-yParaspinal muscle characteristics on MRI in degenerative lumbar spine with normal bone density, osteopenia and osteoporosis: a case-control studyGengyu Han0Da Zou1Zexiang Liu2Siyu Zhou3Wei Li4Chunjie Gong5Zhuoran Sun6Weishi Li7Department of Orthopaedics, Peking University Third HospitalDepartment of Orthopaedics, Peking University Third HospitalDepartment of Orthopaedics, Peking University Third HospitalDepartment of Orthopaedics, Peking University Third HospitalDepartment of Orthopaedics, Peking University Third HospitalDepartment of Orthopaedics, Peking University Third HospitalDepartment of Orthopaedics, Peking University Third HospitalDepartment of Orthopaedics, Peking University Third HospitalAbstract Background To investigate the difference of paraspinal muscles in patients with normal bone density, osteopenia and osteoporosis. Methods Patients undergoing surgery for lumbar spinal stenosis were included. Thirty-eight patients with osteoporosis were matched to patients with osteopenia and patients with normal bone density in a 1:1 manner according to WHO criteria. Dual-energy X-ray absorptiometry (DXA) scans and lumbar CT were performed preoperatively to measure the BMD of lumbar, femur and hip and HU values of L1-L4 respectively. The relative total cross-sectional area (rTCSA) and fat infiltration (FI) of multifidus (MF) and erector spinae (ES), and the relative functional CSA (rFCSA) of psoas major (PS) were measured at L4–5 and L5-S level on preoperative MRI. Results Osteoporotic patients showed lower BMI, higher MF FI and higher ES FI when compared with normal bone density group (25.57 ± 3.71 vs 27.46 ± 3.11; 0.38 ± 0.1 vs 0.32 ± 0.08; 0.33 ± 0.1 vs 0.28 ± 0.08; all adjusted p < 0.05). Both the MF FI and ES FI were significantly correlated with lumbar T-score (r = − 0.223, p < 0.05; r = − 0.208, p < 0.05) and the averaged lumbar HU value (r = − 0.305, p < 0.01; r = − 0.239, p < 0.05). Conclusions Osteoporosis and paraspinal muscle degeneration might interact with each other and coexist in patients with degenerative lumbar diseases. It is recommended that the paraspinal muscle degeneration should be considered simultaneously when finding a patient with low bone mass before surgery.https://doi.org/10.1186/s12891-022-05036-yBone mineral densityHounsfield units valueMagnetic resonance imagingOsteoporosisParaspinal muscle |
| spellingShingle | Gengyu Han Da Zou Zexiang Liu Siyu Zhou Wei Li Chunjie Gong Zhuoran Sun Weishi Li Paraspinal muscle characteristics on MRI in degenerative lumbar spine with normal bone density, osteopenia and osteoporosis: a case-control study BMC Musculoskeletal Disorders Bone mineral density Hounsfield units value Magnetic resonance imaging Osteoporosis Paraspinal muscle |
| title | Paraspinal muscle characteristics on MRI in degenerative lumbar spine with normal bone density, osteopenia and osteoporosis: a case-control study |
| title_full | Paraspinal muscle characteristics on MRI in degenerative lumbar spine with normal bone density, osteopenia and osteoporosis: a case-control study |
| title_fullStr | Paraspinal muscle characteristics on MRI in degenerative lumbar spine with normal bone density, osteopenia and osteoporosis: a case-control study |
| title_full_unstemmed | Paraspinal muscle characteristics on MRI in degenerative lumbar spine with normal bone density, osteopenia and osteoporosis: a case-control study |
| title_short | Paraspinal muscle characteristics on MRI in degenerative lumbar spine with normal bone density, osteopenia and osteoporosis: a case-control study |
| title_sort | paraspinal muscle characteristics on mri in degenerative lumbar spine with normal bone density osteopenia and osteoporosis a case control study |
| topic | Bone mineral density Hounsfield units value Magnetic resonance imaging Osteoporosis Paraspinal muscle |
| url | https://doi.org/10.1186/s12891-022-05036-y |
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