Non-enzymatic role of SOD1 in intestinal stem cell growth
Abstract Superoxide dismutase 1 (SOD1) modulates intestinal barrier integrity and intestinal homeostasis as an antioxidant enzyme. Intestinal homeostasis is maintained by the intestinal stem cells (ISCs). However, whether and how SOD1 regulates ISCs is unknown. In this study, we established intestin...
Main Authors: | Ying-Chao Wang, Xiao-Xu Leng, Cheng-Bei Zhou, Shi-Yuan Lu, Chi Kwan Tsang, Jie Xu, Ming-Ming Zhang, Hui-Min Chen, Jing-Yuan Fang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-10-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-05267-w |
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