Combined effects of MSU crystals injection and high fat-diet feeding on the establishment of a gout model in C57BL/6 mice

Combined effects of MSU crystals injection and high fat-diet feeding on the establishment of a gout model in C57BL/6 mice

Abstract Objective Gout is characterized by inflammatory arthritis with hyperuricaemia and deposition of monosodium urate (MSU) crystals in the joints. Several animal models have been proposed based on MSU crystals injection or high-fat diet feeding; however, neither hyperuricaemia model nor acute g...

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Bibliographic Details
Main Authors: Xiaoying Lin, Tiejuan Shao, Xianghui Wen, Mingzhu Wang, Chengping Wen, Zhixing He
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Advances in Rheumatology
Subjects:
Gout
Animal model
Serum inflammation
Gut microbiota
Combined effects
Online Access:http://link.springer.com/article/10.1186/s42358-020-00155-3

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