The Role of Imaging of Lymphatic System to Prevent Cancer Related Lymphedema
Lymphedema is a progressive chronic condition affecting approximately 250 million people worldwide, a number that is currently underestimated. In Western countries, the most common form of lymphedema of the extremities is cancer-related and less radical surgical intervention is the main option to pr...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-12-01
|
| Series: | Bioengineering |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2306-5354/10/12/1407 |
| _version_ | 1827575610543702016 |
|---|---|
| author | Vincenzo Cuccurullo Marco Rapa Barbara Catalfamo Gianluca Gatta Graziella Di Grezia Giuseppe Lucio Cascini |
| author_facet | Vincenzo Cuccurullo Marco Rapa Barbara Catalfamo Gianluca Gatta Graziella Di Grezia Giuseppe Lucio Cascini |
| author_sort | Vincenzo Cuccurullo |
| collection | DOAJ |
| description | Lymphedema is a progressive chronic condition affecting approximately 250 million people worldwide, a number that is currently underestimated. In Western countries, the most common form of lymphedema of the extremities is cancer-related and less radical surgical intervention is the main option to prevent it. Standardized protocols in the areas of diagnosis, staging and treatment are strongly required to address this issue. The aim of this study is to review the main diagnostic methods, comparing new emerging procedures to lymphoscintigraphy, considered as the golden standard to date. The roles of Magnetic Resonance Lymphangiography (MRL) or indocyanine green ICG lymphography are particularly reviewed in order to evaluate diagnostic accuracy, potential associations with lymphoscintigraphy, and future directions guided by AI protocols. The use of imaging to treat lymphedema has benefited from new techniques in the area of lymphatic vessels anatomy; these perspectives have become of value in many clinical scenarios to prevent cancer-related lymphedema. |
| first_indexed | 2024-03-08T20:59:30Z |
| format | Article |
| id | doaj.art-3db33fc39b014f5aa83bac1c3c309982 |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-08T20:59:30Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj.art-3db33fc39b014f5aa83bac1c3c3099822023-12-22T13:54:11ZengMDPI AGBioengineering2306-53542023-12-011012140710.3390/bioengineering10121407The Role of Imaging of Lymphatic System to Prevent Cancer Related LymphedemaVincenzo Cuccurullo0Marco Rapa1Barbara Catalfamo2Gianluca Gatta3Graziella Di Grezia4Giuseppe Lucio Cascini5Department of Precision Medicine, Università della Campania “Luigi Vanvitelli”, 80131 Napoli, ItalyDepartment of Precision Medicine, Università della Campania “Luigi Vanvitelli”, 80131 Napoli, ItalyNuclear Medicine Unit, Department of Diagnostic Imaging, Magna Graecia University of Catanzaro, 88100 Catanzaro, ItalyDepartment of Precision Medicine, Università della Campania “Luigi Vanvitelli”, 80131 Napoli, ItalyRadiology Department, ASL Avellino, 83100 Avellino, ItalyNuclear Medicine Unit, Department of Diagnostic Imaging, Magna Graecia University of Catanzaro, 88100 Catanzaro, ItalyLymphedema is a progressive chronic condition affecting approximately 250 million people worldwide, a number that is currently underestimated. In Western countries, the most common form of lymphedema of the extremities is cancer-related and less radical surgical intervention is the main option to prevent it. Standardized protocols in the areas of diagnosis, staging and treatment are strongly required to address this issue. The aim of this study is to review the main diagnostic methods, comparing new emerging procedures to lymphoscintigraphy, considered as the golden standard to date. The roles of Magnetic Resonance Lymphangiography (MRL) or indocyanine green ICG lymphography are particularly reviewed in order to evaluate diagnostic accuracy, potential associations with lymphoscintigraphy, and future directions guided by AI protocols. The use of imaging to treat lymphedema has benefited from new techniques in the area of lymphatic vessels anatomy; these perspectives have become of value in many clinical scenarios to prevent cancer-related lymphedema.https://www.mdpi.com/2306-5354/10/12/1407lymphedemaimaginglymphoscintigraphylymphangiographyMRLARM |
| spellingShingle | Vincenzo Cuccurullo Marco Rapa Barbara Catalfamo Gianluca Gatta Graziella Di Grezia Giuseppe Lucio Cascini The Role of Imaging of Lymphatic System to Prevent Cancer Related Lymphedema Bioengineering lymphedema imaging lymphoscintigraphy lymphangiography MRL ARM |
| title | The Role of Imaging of Lymphatic System to Prevent Cancer Related Lymphedema |
| title_full | The Role of Imaging of Lymphatic System to Prevent Cancer Related Lymphedema |
| title_fullStr | The Role of Imaging of Lymphatic System to Prevent Cancer Related Lymphedema |
| title_full_unstemmed | The Role of Imaging of Lymphatic System to Prevent Cancer Related Lymphedema |
| title_short | The Role of Imaging of Lymphatic System to Prevent Cancer Related Lymphedema |
| title_sort | role of imaging of lymphatic system to prevent cancer related lymphedema |
| topic | lymphedema imaging lymphoscintigraphy lymphangiography MRL ARM |
| url | https://www.mdpi.com/2306-5354/10/12/1407 |
| work_keys_str_mv | AT vincenzocuccurullo theroleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT marcorapa theroleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT barbaracatalfamo theroleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT gianlucagatta theroleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT grazielladigrezia theroleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT giuseppeluciocascini theroleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT vincenzocuccurullo roleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT marcorapa roleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT barbaracatalfamo roleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT gianlucagatta roleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT grazielladigrezia roleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema AT giuseppeluciocascini roleofimagingoflymphaticsystemtopreventcancerrelatedlymphedema |