Profiling the metabolic disorder and detection of colorectal cancer based on targeted amino acids metabolomics

Profiling the metabolic disorder and detection of colorectal cancer based on targeted amino acids metabolomics

Abstract Background The morbidity of cancer keeps growing worldwide, and among that, the colorectal cancer (CRC) has jumped to third. Existing early screening tests for CRC are limited. The aim of this study was to develop a diagnostic strategy for CRC by plasma metabolomics. Methods A targeted amin...

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Bibliographic Details
Main Authors: Yang Yang, Zhipeng Wang, Xinxing Li, Jianfeng Lv, Renqian Zhong, Shouhong Gao, Feng Zhang, Wansheng Chen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Colorectal cancer
Amino acids
Targeted metabolomics
Diagnostic model
Transcriptome
Online Access:https://doi.org/10.1186/s12967-023-04604-7

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