Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery

Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery

Cyclodextrin polymers have high applicability in pharmaceutical formulations due to better biocompatibility, solubility enhancement, loading capacity and controlled drug release than their parent, cyclodextrins. The cytotoxicity and cell uptake of new cationic beta-cyclodextrin monomers and polymers...

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Bibliographic Details
Main Authors: Giovanna Rassu, Silvia Fancello, Marta Roldo, Milo Malanga, Lajos Szente, Rossana Migheli, Elisabetta Gavini, Paolo Giunchedi
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
cationic cyclodextrin
cyclodextrin polymer
epichlorohydrin cross-linker
nasal delivery
cytotoxicity
cell uptake
Online Access:https://www.mdpi.com/1999-4923/12/7/658

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