Circulating miR-16-5p, miR-92a-3p, and miR-451a in Plasma from Lung Cancer Patients: Potential Application in Early Detection and a Regulatory Role in Tumorigenesis Pathways

Circulating miR-16-5p, miR-92a-3p, and miR-451a in Plasma from Lung Cancer Patients: Potential Application in Early Detection and a Regulatory Role in Tumorigenesis Pathways

Background: Micro(mi)RNAs, potent gene expression regulators associated with tumorigenesis, are stable, abundant circulating molecules, and detectable in plasma. Thus, miRNAs could potentially be useful in early lung cancer detection. We aimed to identify circulating miRNA signatures in plasma from...

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Bibliographic Details
Main Authors: Patricia P. Reis, Sandra A. Drigo, Robson F. Carvalho, Rainer Marco Lopez Lapa, Tainara F. Felix, Devalben Patel, Dangxiao Cheng, Melania Pintilie, Geoffrey Liu, Ming-Sound Tsao
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
lung cancer
lung adenocarcinoma
lung squamous cell carcinoma
microRNAs
plasma
liquid biopsy
Online Access:https://www.mdpi.com/2072-6694/12/8/2071

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