Compartmentalization of Resistance-Associated Substitutions in HIV/HCV-Infected Patients: Possible Correlation with Infecting HCV Genotype

Compartmentalization of Resistance-Associated Substitutions in HIV/HCV-Infected Patients: Possible Correlation with Infecting HCV Genotype

Resistance-associated substitutions (RASs) may exist prior to treatment and contribute to the failure of treatment with direct-acting antivirals (DAAs). As the major site of HCV replication, naturally occurring variants with RASs may segregate into the liver. In the present study, we performed viral...

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Bibliographic Details
Main Authors: Giulia Morsica, Riccardo Vercesi, Hamid Hasson, Emanuela Messina, Caterina Uberti-Foppa, Sabrina Bagaglio
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Viruses
Subjects:
liver
plasma
compartmentalization
resistance
HCV
HIV
Online Access:https://www.mdpi.com/1999-4915/13/8/1486

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