A new frontier in temporomandibular joint osteoarthritis treatment: Exosome-based therapeutic strategy

A new frontier in temporomandibular joint osteoarthritis treatment: Exosome-based therapeutic strategy

Temporomandibular joint osteoarthritis (TMJOA) is a debilitating degenerative disease with high incidence, deteriorating quality of patient life. Currently, due to ambiguous etiology, the traditional clinical strategies of TMJOA emphasize on symptomatic treatments such as pain relief and inflammatio...

Full description

Bibliographic Details
Main Authors:	Wenxiu Yuan, Yange Wu, Maotuan Huang, Xueman Zhou, Jiaqi Liu, Yating Yi, Jun Wang, Jin Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	temporomandibular joint osteoarthritis Exosome mesenchymal stem cell therapeutic strategy optimization in bioengineering
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2022.1074536/full

Similar Items

Enhancement of the therapeutic efficacy of mesenchymal stem cell-derived exosomes in osteoarthritis
by: Zehao Zhang, et al.
Published: (2023-09-01)

Strontium–Alix interaction enhances exosomal miRNA selectively loading in synovial MSCs for temporomandibular joint osteoarthritis treatment
by: Wenxiu Yuan, et al.
Published: (2025-02-01)

Interdisciplinary Approach to the Temporomandibular Joint Osteoarthritis—Review of the Literature
by: Marcin Derwich, et al.
Published: (2020-05-01)

Osteoarthritis of the Temporomandibular Joint: A Narrative Overview
by: Caroline Mélou, et al.
Published: (2022-12-01)

Burn-synovectomy mouse model for temporomandibular joint osteoarthritis
by: Ginny Ching-Yun Hsu
Published: (2024-03-01)

Exosomes treating osteoarthritis: hope with challenge
by: Congxiao Wu, et al.
Published: (2023-01-01)

The application of exosomes in the early diagnosis and treatment of osteoarthritis
by: Anjing Chen, et al.
Published: (2023-04-01)

Characterization of human placenta-derived exosome (pExo) as a potential osteoarthritis disease modifying therapeutic
by: Chenfei Huang, et al.
Published: (2023-11-01)

Observational study of temporomandibular joint pain in osteoarthritis patients
by: Sahul Hameed Abdul Samad, et al.
Published: (2015-01-01)

Exosomes derived from MSC as drug system in osteoarthritis therapy
by: Shuzhan Wen, et al.
Published: (2024-03-01)

Unveiling MRI-based structural phenotypes in temporomandibular joint osteoarthritis: implications for clinical practice and research
by: Ricardo de Souza TESCH, et al.
Published: (2024-09-01)

Mesenchymal Stem Cell-Derived Exosomes and Their Therapeutic Potential for Osteoarthritis
by: Gi Beom Kim, et al.
Published: (2021-04-01)

Engineering exosomes derived from TNF-α preconditioned IPFP-MSCs enhance both yield and therapeutic efficacy for osteoarthritis
by: Jiangyi Wu, et al.
Published: (2024-09-01)

Advancing Osteoarthritis Treatment: The Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes and Biomaterial Integration
by: Chung-Hua Chu, et al.
Published: (2024-10-01)

Orally Administered NSAIDs—General Characteristics and Usage in the Treatment of Temporomandibular Joint Osteoarthritis—A Narrative Review
by: Marcin Derwich, et al.
Published: (2021-03-01)

Engineering of MSC-Derived Exosomes: A Promising Cell-Free Therapy for Osteoarthritis
by: Jin Cheng, et al.
Published: (2022-07-01)

Efficacy analysis of splint combined with platelet-rich plasma in the treatment of temporomandibular joint osteoarthritis
by: Chuan-Bin Wu, et al.
Published: (2022-11-01)

Can intra-articular daidzein injection reduce oxidative damage and early osteoarthritis in a rabbit temporomandibular joint model?
by: Gokce Elif Erdayandi, et al.
Published: (2024-10-01)

Hypoxia-treated adipose mesenchymal stem cell-derived exosomes attenuate lumbar facet joint osteoarthritis
by: Jinyun Zhao, et al.
Published: (2023-09-01)

Potential pathological and molecular mechanisms of temporomandibular joint osteoarthritis
by: Zhang Juan, et al.
Published: (2023-07-01)

Association of HMGB1 levels in synovial fluid with the severity of temporomandibular joint osteoarthritis
by: Bo Shao, et al.
Published: (2023-03-01)

Akt2 inhibition alleviates temporomandibular joint osteoarthritis by preventing subchondral bone loss
by: Shi-Yang Feng, et al.
Published: (2025-02-01)

Chondrogenic Potential of Human Umbilical Cord Mesenchymal Stem Cells Cultured with Exosome-Depleted Fetal Bovine Serum in an Osteoarthritis Mouse Model
by: Yu-Hsun Chang, et al.
Published: (2022-11-01)

Critical signaling molecules in the temporomandibular joint osteoarthritis under different magnitudes of mechanical stimulation
by: Yuqi Liu, et al.
Published: (2024-07-01)

Mechanisms and therapeutic prospects of mesenchymal stem cells-derived exosomes for tendinopathy
by: Yuxiang Zhang, et al.
Published: (2023-10-01)

Mesenchymal stem cell-derived exosomes as a promising cell-free therapy for knee osteoarthritis
by: Danni Luo, et al.
Published: (2024-01-01)

Polyphenols as Potential Agents in the Management of Temporomandibular Disorders
by: Stefania Moccia, et al.
Published: (2020-07-01)

Bioengineered MSC-derived exosomes in skin wound repair and regeneration
by: Hanxing Zhao, et al.
Published: (2023-02-01)

Mesenchymal stromal cell-based therapy for cartilage regeneration in knee osteoarthritis
by: Xiao-Na Xiang, et al.
Published: (2022-01-01)

A Young Patient with Temporomandibular Joint Osteoarthritis: Case Report
by: Ema Vrbanović, et al.
Published: (2017-01-01)

Progress of research on the role of primary cilia in cartilage degeneration in temporomandibular joint osteoarthritis
by: LI Gongchen, HU Ziyue, SUN Yao
Published: (2024-06-01)

Low frequency pulsed electromagnetic fields exposure alleviate the abnormal subchondral bone remodeling at the early stage of temporomandibular joint osteoarthritis
by: Yuanjun Ma, et al.
Published: (2022-11-01)

Association between Sleep Disorders and Sleep Quality in Patients with Temporomandibular Joint Osteoarthritis: A Systematic Review
by: Eleuterio A. Sánchez Romero, et al.
Published: (2022-08-01)

Long-term haplodeficency of DSPP causes temporomandibular joint osteoarthritis in mice
by: Qilin Liu, et al.
Published: (2024-05-01)

Detection and Severity Assessment of Temporomandibular Joint Osteoarthritic Changes in Patients with Temporomandibular Disorders Using CBCT
by: Kharman Khidhr Rahman, et al.
Published: (2024-12-01)

COMPLEX TREATMENT OF PATIENTS WITH OSTEOARTHRITIS OF THE TEMPOROMANDIBULAR JOINT
by: VP P Potapov, et al.
Published: (2016-06-01)

Role of MicroRNA, LncRNA, and Exosomes in the Progression of Osteoarthritis: A Review of Recent Literature
by: Fang Xie, et al.
Published: (2020-06-01)

Whole-transcriptome sequencing and ceRNA interaction network of temporomandibular joint osteoarthritis
by: Fan Wu, et al.
Published: (2022-10-01)

Effect of medical ozone injection therapy on temporomandibular joint osteoarthritis and its pain in rats
by: LU Caixia, ZHANG Simin, Nigeayi·AIHEMAITI , LI Xueer, CHEN Zeyuan, Maimaitituxun·TUERDI
Published: (2024-05-01)

Injectable hyperbranched PEG crosslinked hyaluronan hydrogel microparticles containing mir-99a-3p modified subcutaneous ADSCs-derived exosomes was beneficial for long-term treatment of osteoarthritis
by: Zhaowei Yin, et al.
Published: (2023-12-01)