EPHB4-RASA1-Mediated Negative Regulation of Ras-MAPK Signaling in the Vasculature: Implications for the Treatment of EPHB4- and RASA1-Related Vascular Anomalies in Humans
Ephrin receptors constitute a large family of receptor tyrosine kinases in mammals that through interaction with cell surface-anchored ephrin ligands regulate multiple different cellular responses in numerous cell types and tissues. In the cardiovascular system, studies performed in vitro and in viv...
Auteurs principaux: | , , , |
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Format: | Article |
Langue: | English |
Publié: |
MDPI AG
2023-01-01
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Collection: | Pharmaceuticals |
Sujets: | |
Accès en ligne: | https://www.mdpi.com/1424-8247/16/2/165 |