Inorganic biomaterials‐based bioinks for three‐dimensional bioprinting of regenerative scaffolds

Abstract The application of inorganic biomaterials in regenerative medicine is increasingly expanded. Taking advantages of attractive properties of the inorganic biomaterials, sorts of functional bioinks have been developed based on inorganic biomaterials and were applied to construct inorganic/orga...

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Main Authors: Chen Qin, Chengtie Wu
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:View
Subjects:
Online Access:https://doi.org/10.1002/VIW.20210018
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author Chen Qin
Chengtie Wu
author_facet Chen Qin
Chengtie Wu
author_sort Chen Qin
collection DOAJ
description Abstract The application of inorganic biomaterials in regenerative medicine is increasingly expanded. Taking advantages of attractive properties of the inorganic biomaterials, sorts of functional bioinks have been developed based on inorganic biomaterials and were applied to construct inorganic/organic/cell‐laden systems for tissue regeneration via 3D bioprinting technology. In this review, we aim to summarize the existing inorganic biomaterials‐based bioinks (referred to as “inorganic‐bioinks”) for 3D bioprinting regenerative scaffolds. We introduce the recently developed inorganic‐bioinks from the perspective of the function of bioinks, and especially highlight the incorporation of inorganic biomaterials improving the printability, mechanical strength, and bioactivity of the bioinks for different tissue regeneration. Subsequently, the current applications of the inorganic‐bioinks in constructing 3D cell‐laden scaffolds for tissue regeneration are presented. Finally, challenges and prospects for the inorganic biomaterials‐based bioprinting strategy are discussed.
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spelling doaj.art-3dc122bcd013445e964895f6ea3cd9812022-12-22T02:12:40ZengWileyView2688-39882688-268X2022-07-0134n/an/a10.1002/VIW.20210018Inorganic biomaterials‐based bioinks for three‐dimensional bioprinting of regenerative scaffoldsChen Qin0Chengtie Wu1State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai ChinaState Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai ChinaAbstract The application of inorganic biomaterials in regenerative medicine is increasingly expanded. Taking advantages of attractive properties of the inorganic biomaterials, sorts of functional bioinks have been developed based on inorganic biomaterials and were applied to construct inorganic/organic/cell‐laden systems for tissue regeneration via 3D bioprinting technology. In this review, we aim to summarize the existing inorganic biomaterials‐based bioinks (referred to as “inorganic‐bioinks”) for 3D bioprinting regenerative scaffolds. We introduce the recently developed inorganic‐bioinks from the perspective of the function of bioinks, and especially highlight the incorporation of inorganic biomaterials improving the printability, mechanical strength, and bioactivity of the bioinks for different tissue regeneration. Subsequently, the current applications of the inorganic‐bioinks in constructing 3D cell‐laden scaffolds for tissue regeneration are presented. Finally, challenges and prospects for the inorganic biomaterials‐based bioprinting strategy are discussed.https://doi.org/10.1002/VIW.202100183D bioprintingbioinkinorganic biomaterialstissue regeneration
spellingShingle Chen Qin
Chengtie Wu
Inorganic biomaterials‐based bioinks for three‐dimensional bioprinting of regenerative scaffolds
View
3D bioprinting
bioink
inorganic biomaterials
tissue regeneration
title Inorganic biomaterials‐based bioinks for three‐dimensional bioprinting of regenerative scaffolds
title_full Inorganic biomaterials‐based bioinks for three‐dimensional bioprinting of regenerative scaffolds
title_fullStr Inorganic biomaterials‐based bioinks for three‐dimensional bioprinting of regenerative scaffolds
title_full_unstemmed Inorganic biomaterials‐based bioinks for three‐dimensional bioprinting of regenerative scaffolds
title_short Inorganic biomaterials‐based bioinks for three‐dimensional bioprinting of regenerative scaffolds
title_sort inorganic biomaterials based bioinks for three dimensional bioprinting of regenerative scaffolds
topic 3D bioprinting
bioink
inorganic biomaterials
tissue regeneration
url https://doi.org/10.1002/VIW.20210018
work_keys_str_mv AT chenqin inorganicbiomaterialsbasedbioinksforthreedimensionalbioprintingofregenerativescaffolds
AT chengtiewu inorganicbiomaterialsbasedbioinksforthreedimensionalbioprintingofregenerativescaffolds