The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer
Prostate cancer is the second most frequently occurring cancer diagnosed among males. Recent preclinical evidence implicates cannabinoids as powerful regulators of cell growth and differentiation. In this review, we focused on studies that demonstrated anticancer effects of cannabinoids and their po...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/13/16/4107 |
| _version_ | 1797524433850597376 |
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| author | Kanika Singh Nazim Nassar Ava Bachari Ellen Schanknecht Srinivasareddy Telukutla Roby Zomer Terrence J. Piva Nitin Mantri |
| author_facet | Kanika Singh Nazim Nassar Ava Bachari Ellen Schanknecht Srinivasareddy Telukutla Roby Zomer Terrence J. Piva Nitin Mantri |
| author_sort | Kanika Singh |
| collection | DOAJ |
| description | Prostate cancer is the second most frequently occurring cancer diagnosed among males. Recent preclinical evidence implicates cannabinoids as powerful regulators of cell growth and differentiation. In this review, we focused on studies that demonstrated anticancer effects of cannabinoids and their possible mechanisms of action in prostate cancer. Besides the palliative effects of cannabinoids, research from the past two decades has demonstrated their promising potential as antitumor agents in a wide variety of cancers. This analysis may provide pharmacological insights into the selection of specific cannabinoids for the development of antitumor drugs for the treatment of prostate cancer. |
| first_indexed | 2024-03-10T08:56:21Z |
| format | Article |
| id | doaj.art-3dc4250e8c224e589f0622b15821257f |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-10T08:56:21Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-3dc4250e8c224e589f0622b15821257f2023-11-22T07:03:54ZengMDPI AGCancers2072-66942021-08-011316410710.3390/cancers13164107The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate CancerKanika Singh0Nazim Nassar1Ava Bachari2Ellen Schanknecht3Srinivasareddy Telukutla4Roby Zomer5Terrence J. Piva6Nitin Mantri7The Pangenomics Lab, School of Science, RMIT University, Bundoora, VIC 3083, AustraliaSchool of Health and Biomedical Sciences, RMIT University, Bundoora, VIC 3083, AustraliaThe Pangenomics Lab, School of Science, RMIT University, Bundoora, VIC 3083, AustraliaThe Pangenomics Lab, School of Science, RMIT University, Bundoora, VIC 3083, AustraliaThe Pangenomics Lab, School of Science, RMIT University, Bundoora, VIC 3083, AustraliaMGC Pharmaceuticals Limited, West Perth, WA 6005, AustraliaSchool of Health and Biomedical Sciences, RMIT University, Bundoora, VIC 3083, AustraliaThe Pangenomics Lab, School of Science, RMIT University, Bundoora, VIC 3083, AustraliaProstate cancer is the second most frequently occurring cancer diagnosed among males. Recent preclinical evidence implicates cannabinoids as powerful regulators of cell growth and differentiation. In this review, we focused on studies that demonstrated anticancer effects of cannabinoids and their possible mechanisms of action in prostate cancer. Besides the palliative effects of cannabinoids, research from the past two decades has demonstrated their promising potential as antitumor agents in a wide variety of cancers. This analysis may provide pharmacological insights into the selection of specific cannabinoids for the development of antitumor drugs for the treatment of prostate cancer.https://www.mdpi.com/2072-6694/13/16/4107prostate cancercannabiscannabinoidscannabinoid receptorscancer |
| spellingShingle | Kanika Singh Nazim Nassar Ava Bachari Ellen Schanknecht Srinivasareddy Telukutla Roby Zomer Terrence J. Piva Nitin Mantri The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer Cancers prostate cancer cannabis cannabinoids cannabinoid receptors cancer |
| title | The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer |
| title_full | The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer |
| title_fullStr | The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer |
| title_full_unstemmed | The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer |
| title_short | The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer |
| title_sort | pathophysiology and the therapeutic potential of cannabinoids in prostate cancer |
| topic | prostate cancer cannabis cannabinoids cannabinoid receptors cancer |
| url | https://www.mdpi.com/2072-6694/13/16/4107 |
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