Interleukins 4 and 13 and Their Receptors Are Differently Expressed in Gastrointestinal Tract Cancers, Depending on the Anatomical Site and Disease Advancement, and Improve Colon Cancer Cell Viability and Motility

Interleukins 4 and 13 and Their Receptors Are Differently Expressed in Gastrointestinal Tract Cancers, Depending on the Anatomical Site and Disease Advancement, and Improve Colon Cancer Cell Viability and Motility

Immunosuppressive interleukins (IL)-4 and 13 may directly promote cancer but neither their status nor role in gastrointestinal tract is clarified. We aim at quantifying ILs and their receptors in paired normal-tumor samples (<i>n</i> = 49/51) and sera (<i>n</i> = 263), using...

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Bibliographic Details
Main Authors: Iwona Bednarz-Misa, Dorota Diakowska, Izabela Szczuka, Paulina Fortuna, Agnieszka Kubiak, Joanna Rosińczuk, Małgorzata Krzystek-Korpacka
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
colorectal cancer
esophageal squamous cell carcinoma
gastric adenocarcinoma
immunotherapy
molecular margin
interleukin
Online Access:https://www.mdpi.com/2072-6694/12/6/1463

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